research Exosomes: Historical Evolution and Emerging Roles in Dermatology
Exosomes are important for skin treatments and hair growth but need more research for safe and effective use.
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research Melanocytes in Regenerative Medicine Applications and Disease Modeling
Melanocytes are important for normal body functions and have potential uses in regenerative medicine and disease treatment.
research The JAK/STAT Signaling Pathway: From Bench to Clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research New Developments in Our Understanding of Acne Pathogenesis and Treatment
We now understand more about what causes acne and this could lead to better, more personalized treatments.
research Therapeutic, Prophylactic, and Functional Use of Probiotics: A Current Perspective
Probiotics show promise for health benefits but need more research to understand how they work.
research Application of Acyzol in the Context of Zinc Deficiency and Perspectives
Acyzol could help treat conditions caused by zinc deficiency.
research Roles of Steroid Receptors in the Lung and COVID-19
Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.
research Nano-Pulse Stimulation Therapy Is Superior to Cryoablation in Clearing Murine Melanoma Tumors
Nano-Pulse Stimulation™ Therapy is more effective and less damaging than cryoablation for treating melanoma tumors in mice.
research Improved Humoral Immunity and Protection Against Influenza Virus Infection With a 3D Porous Biomaterial Vaccine
A new vaccine using a porous scaffold boosts immunity and protects against the flu better than traditional methods.
research Exploiting the Origins of Ras-Mediated Squamous Cell Carcinoma to Develop Novel Therapeutic Interventions
Researchers found that hair follicle stem cells can become squamous cell carcinoma due to Ras activation, which could lead to new treatments.
research Topical Delivery of Tofacitinib in Dermatology: The Promise of a Novel Therapeutic Class Using Biodegradable Dendritic Polyglycerol Sulfates
A new carrier improves skin delivery of tofacitinib for treating inflammatory skin diseases.
research Human Regulatory T Cells: Role in Autoimmune Skin Diseases and Post-Transplant Nonmelanoma Skin Cancers
Understanding how Regulatory T Cells work could help create treatments for certain skin diseases and cancers.
research Lymphatic Vasculature and Hair Follicle Regeneration
Lymphatic vessels help hair follicles regenerate by interacting with stem cells.
research Intestinal Intraepithelial Lymphocytes: Sentinels of the Mucosal Barrier
Intestinal intraepithelial lymphocytes are crucial for gut immunity and maintaining the mucosal barrier.
research Expression of Mu-Opiate Receptor in Human Epidermis and Keratinocytes
μ-opiate receptors in skin cells may affect skin health and healing.
research Protective Role of Melatonin and Its Metabolites in Skin Aging
Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.
research Catalytic Antibodies in Normal and Systemic Lupus Erythematosus
Catalytic antibodies are early indicators and active participants in the development of systemic lupus erythematosus.
research Phenotypic Analysis of T-Cells in Extensive Alopecia Areata Scalp Suggests Partial Tolerance
T-cells in alopecia areata scalp show abnormal regulation, leading to less inflammation.
research Heat Treatment Increases the Incidence of Alopecia Areata in the C3H/HeJ Mouse Model
Heat treatment increases hair loss in certain mice.
research Endoplasmic Reticulum in Health and Disease: The 12th International Calreticulin Workshop, Delphi, Greece
The workshop discussed the role of a protein called calreticulin in health and disease, its potential as a treatment target, and its possible use as a disease marker.
research MAIT Cells in COVID-19: Heroes, Villains, or Both?
MAIT cells may help fight COVID-19 but also contribute to severe inflammation.
research Chitosan Hydrogel as Tissue Engineering Scaffolds for Vascular Regeneration Applications
Chitosan hydrogels are promising for repairing blood vessels but need improvements in strength and compatibility.
research A Network Pharmacology-Based Approach to Explore Mechanism of Action of Medicinal Herbs for Alopecia Treatment
Medicinal herbs might treat hair loss by affecting genes and pathways related to lipid and glycerophospholipid metabolism.
research Network-Based Approaches Reveal Potential Therapeutic Targets for Host-Directed Antileishmanial Therapy Driving Drug Repurposing
Researchers identified five new potential targets for leishmaniasis treatment, suggesting repurposing existing drugs could be effective.
research Stem Cell Secretome as a Mechanism for Restoring Hair Loss Due to Stress, Particularly Alopecia Areata: Narrative Review
Stem cells and their secretions could potentially treat stress-induced hair loss, but more human trials are needed.
research 3D Spheroid Human Dermal Papilla Cell as an Effective Model for the Screening of Hair Growth Promoting Compounds: Examples of Minoxidil and 3,4,5-Tri-O-Caffeoylquinic Acid (TCQA)
3D cell cultures are better for testing hair growth treatments than 2D cultures.
research Application of Mesenchymal Stem Cells for Anti-Senescence and Clinical Challenges
Mesenchymal stem cells could help treat aging-related diseases better than current methods.
research Exosomes: A Promising Strategy for Repair, Regeneration and Treatment of Skin Disorders
Exosomes could be a promising way to help repair skin and treat skin disorders.
research Recent Advances in Genome-Editing Technology with CRISPR/Cas9 Variants and Stimuli-Responsive Targeting Approaches within Tumor Cells: A Future Perspective of Cancer Management
New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.
research Bioengineered Skin Organoids: From Development to Applications
Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.