61 citations
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September 2010 in “Genomics” This study found distinct gene expression profiles in alopecia areata-affected skin, suggesting T-cell mediated immune responses and unique gene profiles between different stages of the disease.
January 2023 in “Tehnika” This article discusses the challenges in diagnosing and treating autoimmune diseases, emphasizing the need for regenerative medicine approaches to address the root causes rather than just suppressing symptoms.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that mitochondrial dysfunction might contribute to the pathogenesis of Lichen planopilaris by triggering a metabolic shift that leads to chronic inflammation and hair follicle damage.
1 citations
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January 2023 in “Middle East Research Journal of Pharmaceutical Sciences” This review discusses the mechanisms and grading challenges of acne vulgaris, highlighting the need for better treatment strategies and reports no new experimental results.
May 2024 in “Journal of Education, Health and Sport” This review article highlights the complexity of treating folliculitis decalvans, emphasizing the role of systemic antibiotics like rifampicin and clindamycin as common treatments, while also discussing promising novel therapies, including biological agents, that require further clinical trials to assess their effectiveness and safety.
November 2023 in “Global Medical Genetics” This case report describes a 1-month-old male infant with Netherton syndrome, characterized by severe hypernatremia, skin and scalp issues, highlighting the syndrome's complications, including growth retardation and infection risks in early life.
June 2026 in “Reproduction and Fertility” In this study, researchers highlighted that PCOS involves not only hormonal imbalances but also significant changes in the microbiome and immune system, which complicate its impact on fertility and suggest potential for new diagnostic and therapeutic strategies.
50 citations
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December 2005 in “European Journal of Immunology” This study found that a specific mutation in the mouse RXRalpha gene significantly impacts immune responses and causes hair loss and skin cysts.
22 citations
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January 2009 in “Advances in experimental medicine and biology” This review discusses the human Nude/SCID phenotype and FOXN1 gene's role in immunological disorders affecting T-cell development but reports no new clinical findings.
This research highlights selenium's critical roles in various biological processes and underscores the potential health impacts of both its deficiency and excess, including increased mortality risk, poor immune function, and neurological issues.
January 2024 in “JAAD case reports” Netherton syndrome can cause severe and chronic vulvovaginal symptoms that may improve with continuous oral contraceptives.
September 1998 in “Journal of The European Academy of Dermatology and Venereology” This review summarizes major surveys on Behcet's disease, highlighting its systemic manifestations, with primary morbidity linked to ocular involvement causing severe vision loss or blindness.
55 citations
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May 2007 in “Australasian journal of dermatology” This case report describes the characteristic clinicopathological features of trichodysplasia spinulosa in two boys with acute lymphocytic leukemia, highlighting its resolution as immune function normalizes.
June 2026 in “Frontiers in Bioengineering and Biotechnology” This review outlines the transition from simple hair follicle organoids to immune-competent microphysiological systems, addressing limitations in replicating native hair follicle immune features and discussing their applications in disease modeling and regenerative medicine.
January 2024 in “International Journal of Homoeopathic Sciences” This abstract outlines the issue of hair loss caused by various factors, including stress and autoimmune disorders like alopecia areata, which results in spot baldness, but does not provide specific study results.
4 citations
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April 2004 in “Medical veritas” This journal serves as a platform for diverse perspectives on vaccine-related issues, but the abstract itself reports no new scientific findings.
February 2024 in “Recima21” This study explored the connections between Covid-19 and hair loss issues like telogen effluvium and alopecia areata, highlighting the virus's potential trigger effect and underscoring the importance of comprehensive post-Covid-19 treatment strategies that consider immune, psychological, and hair cycle factors.
22 citations
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March 1994 in “Journal of Heredity” In this study, researchers identified a mutation in mice that causes hair loss and immune system issues, located on chromosome 18.
January 2024 in “International journal of advanced biochemistry research” In this study, eight dogs with severe itching and skin issues caused by Demodex canis mites showed partial improvement after one month and full recovery in two months following treatment with fluralaner, antibiotics, immune boosters, and omega supplements.
August 2025 in “Quality in Sport” In this review, the authors highlighted the importance of vitamin A for vision, immune function, growth, and skin, noting that deficiency can lead to serious health issues like night blindness and increased infection risk, while excessive intake poses toxicity risks, particularly from supplements.
December 2025 in “Journal of Investigative Dermatology” Immune system issues may contribute to female pattern hair loss.
This research addresses the common concern of hair loss, often seen in post-COVID syndrome and other systemic conditions, and highlights uncertainties around its causes, diagnostic criteria, and the necessity for medical consultation, with implications for patient psychological wellbeing.
7 citations
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November 2018 in “British Journal of Dermatology” Alopecia areata is caused by immune system issues, and JAK inhibitors might help treat it.
48 citations
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April 2010 in “Journal of the European Academy of Dermatology and Venereology” This article reviews gender differences in skin disorders, highlighting variations in disease prevalence and type between sexes, but reports no new findings, emphasizing potential implications for prevention and treatment strategies.
45 citations
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December 2006 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” This review discusses the multifaceted role of vitamin D in the body, noting its influence on calcium balance, hair cycle maintenance, cell proliferation, cardiovascular function, and immune modulation, with no new clinical results reported.
3 citations
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January 2017 in “Chinese Science Bulletin (Chinese Version)” This review discusses the gut-brain-skin axis and its role in skin diseases, advocating for treatments that integrate gut microbiota, mental health, and dietary interventions, but reports no new clinical results.
1 citations
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January 1993 This article discusses zinc deficiency in animal nutrition and highlights the need for zinc supplementation in livestock diets; it reports no new study results.
August 2023 in “Natural Resources for Human Health” This paper offers a detailed overview of B vitamins, detailing their importance for energy, cognition, and metabolism, conditions leading to their deficiencies, symptoms of deficiencies, and the foods rich in these essential nutrients.
Recent discoveries have improved our understanding of hair loss, but challenges in treatment and knowledge among specialists still exist.
This review discusses the potential benefits of Ayurvedic remedies—Withania somnifera, Emblica officinalis, Eclipta alba, and Glycyrrhiza glabra—in treating alopecia, highlighting their mechanisms such as inhibiting 5α-reductase, enhancing blood flow, and modulating hair growth pathways, while noting their advantages like fewer side effects and cost-effectiveness.