research CD123 Immunohistochemistry for Plasmacytoid Dendritic Cells Is Useful in the Diagnosis of Scarring Alopecia
Using CD123 to detect certain immune cells helps diagnose a type of hair loss condition.
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research Biological Significance of FoxN1 Gain-of-Function Mutations During T and B Lymphopoiesis in Juvenile Mice
FoxN1 overexpression in young mice harms immune cell and skin development.
research Inhibition of Established Tuberculin Hypersensitivity by Methotrexate
Methotrexate can temporarily suppress certain immune responses without killing immune cells, potentially helping treat autoimmune diseases.
research Acquired Immunogenicity of DNA After Modification with Malondialdehyde in Patients with Alopecia Areata
Malondialdehyde-modified DNA may trigger an immune response in alopecia areata patients.
research Evaluation of Platelet-Rich Plasma on Hair Regrowth and Lesional T-Cell Cytokine Expression in Alopecia Areata: A Randomized Observer-Blinded, Placebo-Controlled, Split-Head Pilot Study
Platelet-rich plasma may help restore immune balance in bald patches, but its effectiveness in treating hair loss is limited.
research Bioactivity Guided Isolation and Characterization of the Phytoconstituents from Tridax Procumbens
Tridax procumbens plant parts boost immune response in mice.
research Extra Virgin Olive Oil as Nutritional Therapeutic Immune Enhancer
Extra virgin olive oil may boost the immune system and help fight infections like COVID-19.
research Trichophyton Tonsurans-Induced Kerion Celsi with Decreased Defensin Expression and Paradoxically Increased Interleukin-17A Production
Terbinafine effectively treated kerion celsi despite disrupted immune responses.
research Activation of TLR3 Enhances Stemness and Immunomodulatory Properties of Periodontal Ligament Stem Cells
Activating TLR3 improves the healing and immune properties of periodontal ligament stem cells.
research Hypothyroidism in Dogs
Hypothyroidism in dogs is usually caused by immune system issues or gland atrophy, affects middle-aged purebreds most, and is treatable with medication.
research Erosive Pustular Dermatosis of the Scalp and Multiple Sclerosis: Just a Coincidence?
EPDS and MS might share an immune-related cause.
research Dermatoscopy Case of the Month: Trichodysplasia Spinulosa
A man with a weakened immune system was diagnosed with a rare skin condition called trichodysplasia spinulosa using skin examination techniques.
research First-Degree Relatives of Patients With Systemic Lupus Erythematosus: Autoreactivity but Not Autoimmunity?
Relatives of lupus patients show signs of immune system activity but not full-blown lupus.
research Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1
Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.
research Systemic Immunotherapies
Systemic immunotherapies are used for immune-related hair loss but not usually for genetic hair loss, unless the patient has both conditions.
research Topical Immunotherapies
Some treatments that modify the immune system might help with certain types of hair loss but haven't been explored for common hair loss alone.
research Deregulation of Toll Like Receptor Signaling and Association With Caveolin-1 in Lichen Planopilaris Reveals a Novel Mechanism in Pathogenesis of Scarring Alopecia
The study suggests that changes in immune system receptors and their interaction with a cell component may be important in the development of a type of hair loss condition.
research Dynamic and Spatial Transcriptional Responses in COVID-19-Related Chilblains
COVID-toes show a unique immune response over time, different from vaccine-related chilblains.
research The Possible Role of PTEN-Induced Kinase 1-Mediated Mitophagy in Regulating Inflammasome Activation in the Pathogenesis of Alopecia Areata
Activating mitophagy may help manage a key immune response involved in the hair loss condition alopecia areata.
research Discovery of Autoantigens in the Hair Loss Disorder Alopecia Areata: Implications of Posttranslational Modifications
Scientists are still unsure what triggers the immune system to attack hair follicles in Alopecia areata.
research Deciphering Pathomechanisms in Solar Urticaria
The study found that skin inflammation and immune response pathways are activated in Solar Urticaria patients after UV exposure, unlike in healthy people.
research Alymphoid Cystic Thymic Dysgenesis - FOXN1 Gene Mutation: A Rare Case Report of Two Siblings
Two siblings had a rare immune disorder caused by a FOXN1 gene mutation.
research Compound Heterozygous Mutations in Forkhead Box N1 (FOXN1) Lead to Severe Immunodeficiency but Normal Hair and Nail Development in Patients
Mutations in the FOXN1 gene cause severe immune issues but don't affect hair and nails.
research Computer-Assisted Epitope Prediction Revealed Potential Autoantigens Associated with Human Alopecia Areata
Melanogenesis-related proteins may trigger immune responses in alopecia areata patients.
research Androgens Inhibit Phagocytosis by Macrophages via the Androgen Receptor In Vitro
Male hormones can decrease the ability of immune cells to fight bacteria.
research Purification and Characterization of an Immuno-Stimulatory Compound from the Water Extract of Royoporus Badius (Pers.) A.B. De.
A new compound from Royoporus badius activates immune cells and induces inflammatory responses.
research Loss of Langerhans Cells in Scar Lesion of Lichen Planopilaris Is Caused by Downregulation of Integrin αvβ6 in the Epidermal Keratinocytes
Scarred skin in lichen planopilaris loses immune cells due to a decrease in a specific protein in skin cells.
research Endoplasmic Reticulum Stress Upregulates NKG2D Ligands in the Hair Follicle
Stress in hair follicle cells increases certain immune-related proteins, which might contribute to hair loss conditions.
research Over- And Ectopic-Expression Of FoxN1 At Early Life Adversely Influences Lymphopoiesis
Early over-expression of FoxN1 harms immune and skin development.
research Autoimmune Diseases and Acquired Von Willebrand Disease in Two Cases of Progeria
Premature aging increases the risk of immune problems and autoimmune diseases.