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Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.

Liposomes show promise for delivering CRISPR for gene editing but face challenges like delivery efficiency and safety concerns.

Blocking cholesterol production may help control hair loss in Primary Cicatricial Alopecia by affecting key regulators.

Certain genes are more active during wound healing in axolotl and Acomys, which could help develop materials that improve human wound healing and regeneration.

Alopecia areata needs more recognition and better treatment access in Latin America to improve patient care and outcomes.

Activating c-Myc in skin causes rapid cell growth and changes, but these effects are reversible.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Creating fully functional artificial skin for chronic wounds is still very challenging.

Wharton’s Jelly stem cells from the umbilical cord improve skin healing and hair growth without scarring.

Different treatments for Hidradenitis suppurativa range from antibiotics and hormonal therapies to surgery, depending on severity.

Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.

Scalp itching is common and hard to diagnose due to the complex nerve structure of the scalp.

New therapies are being developed that target integrin pathways to treat various diseases.

Early diagnosis and a strict gluten-free diet are crucial for children with celiac disease to improve symptoms.

Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.

Adult stem cells are effective and ethically acceptable for treating various diseases.

PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.

The document concludes that Hidradenitis suppurativa is often underdiagnosed, lacks definitive treatment, and requires better awareness and management strategies.

Light therapy can stimulate hair growth and is more effective when started early, but more research is needed on its long-term effects and optimal use.

3D bioprinting improves wound healing by precisely creating scaffolds with living cells and biomaterials, but faces challenges like resolution and speed.

Testosterone may influence COVID-19 severity and outcomes.

Platelet-derived bio-products help in wound healing and tissue regeneration but lack standardized methods, and their use in medicine is growing.

The review suggests that a special cell-derived treatment shows promise for various skin conditions and hair growth but needs more research for confirmation.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.

New hair follicles could be created to treat hair loss.

Lespedeza cuneata extract may help treat enlarged prostate.

Key genes crucial for sheep hair follicle development were identified, aiding fine wool breeding and human hair loss research.

Vitamin D is important for skin health, but more research is needed to understand its full effects and treatment potential.

Hand and forearm transplants can be successful long-term, but they come with challenges like rejection and side effects from immunosuppression.

Using a drug to activate bone marrow stem cells can help the liver regenerate and function better after major surgery in rats.