research Toll-Like Receptor 4 (TLR4): New Insights into Immunity and Aging
TLR4 is important in aging-related diseases and could be a new treatment target.
Search
for
Sort by
Research
450-480 / 1000+ results 
research Novel Therapies for Alopecia Areata: The Era of Rational Drug Development
New targeted therapies for hair loss from alopecia areata show promise, with personalized treatment expected in the future.
research Biomaterials and Stem Cells: Promising Tools in Tissue Engineering and Biomedical Applications
Biomaterials combined with stem cells show promise for improving tissue repair and medical treatments.
research Inhibition of T-Cell Activity in Alopecia Areata: Recent Developments and New Directions
New treatments targeting T-cell pathways are needed for better alopecia areata management.
research Future Directions in the Treatment of Vitiligo
New treatments for vitiligo may focus on protecting melanocyte stem cells from stress and targeting specific pathways involved in the condition.
research Generating Detailed Intercellular Communication Patterns in Psoriasis at the Single-Cell Level Using Social Networking, Pattern Recognition, and Manifold Learning Methods to Optimize Treatment Strategies
New insights into cell communication in psoriasis suggest innovative drug treatments.
research Evaluation of Cardiac Risk Marker Levels in Obese and Non-Obese Patients with Polycystic Ovaries
Obese and non-obese women with PCOS have higher heart risk markers, especially if they are obese.
research Fibroblast Heterogeneity and Tertiary Lymphoid Tissues in the Kidney
Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.
research Formation of the Cornified Envelope
The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.
research Clinical Application of Nonantibiotic Macrolides for Inflammation-Driven Immune Dysfunction in Inflammatory Skin Diseases
Nonantibiotic macrolides show promise for treating various inflammatory skin conditions.
research The Influence of Interferon on Healthy and Diseased Skin
Type I interferons play a key role in the development of various skin diseases.
research Tregs: Where We Are and What Comes Next?
The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.
research Abstracts
New treatments and diagnostic methods for various animal skin conditions showed promising results.
research Efficacy and Safety of Different JAK Inhibitors in the Treatment of Alopecia Areata: A Network Meta-Analysis
Oral baricitinib and ruxolitinib are effective and safe for treating alopecia areata.
research The Role of Tight Junctions in Skin Barrier Function and Dermal Absorption
Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
research Tumor Regression Predicts Higher Risk of Sentinel Node Involvement in Thin Cutaneous Melanomas
Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.
research Group IID, IIE, IIF, and III Secreted Phospholipase A2s
Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
research Hormonal Regulation in Male Androgenetic Alopecia: Sex Hormones and Beyond - Evidence from Recent Genetic Studies
Hormones and genes affect hair growth and male baldness.
research Sublingual Tofacitinib for Alopecia Areata: A Roll-Over Pilot Clinical Trial and Analysis of Pharmacokinetics
The trial showed that a new under-the-tongue treatment for severe hair loss was somewhat effective in a small group of people.
research Practical Approach for Treatment Lines of Alopecia Areata: Review Article
The conclusion is that emotional support and a variety of treatments are important for alopecia areata, but more research is needed.
research Genome-Wide Association Studies for Immunoglobulins in Colostrum and Serum in Chinese Holstein
Selective breeding can enhance immunity in dairy cattle.
research Fisetin Promotes Differentiation, Inhibits Proliferative and Inflammatory Responses in Cultured Human Cells and Alleviates Psoriasiform Dermatitis in Mice
Fisetin may help treat psoriasis and reduce skin inflammation.
research Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
Different types of skin cells play specific roles in development, healing, and cancer.
research COVID-19 and Sex Differences: Mechanisms and Biomarkers
Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.
research Exosomes for Repair, Regeneration, and Rejuvenation
Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.
research The Emerging Role of Janus Kinase Inhibitors in the Treatment of Autoimmune and Inflammatory Diseases
Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.
research Beyond Expectations: The Role of Keratin Intermediate Filament Proteins in Epidermal Integrity
Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
research The Utility of Metformin Therapy in Reproductive-Aged Women with Polycystic Ovary Syndrome
Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.
research Stem Cells Tightly Regulate Dead Cell Clearance to Maintain Tissue Fitness
Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.
research Treatment of Alopecia Areata in Mice by Stimulating Hair Follicles Using Parathyroid Hormone Agonists Linked to a Collagen Binding Domain
A protein combining parathyroid hormone and collagen helped hair regrow in mice with a hair loss condition.