Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study reports that some human cell surface HLA-I molecules (including HLA-B27) can appear without their usual peptide component, potentially altering immune interactions, influencing arthritis development in specific mice models, and exhibiting upregulation in certain cancer cells.

This review discusses the potential of a low-dose comprehensive cyclical nutrient therapy for enhancing hair growth and strengthening hair roots, but reports no new experimental results.

This review explores the potential of cell-mediated drug delivery systems in dermatology, highlighting their ability to target inflamed or diseased skin while discussing applications in diseases like atopic dermatitis and melanoma, along with challenges such as immunogenicity and manufacturing.

This study developed immortalized human hair follicle-derived mesenchymal-like stromal cells (iHF-MSCs) as a consistent source of therapeutic secretome, reporting their superior immunomodulatory and regenerative performance, potentially advancing cell-free therapies for inflammation and tissue repair.

This review discusses the uncertain role of immune factors, particularly autoantibodies, in the development of alopecia areata and emphasizes that identifying key autoantigens could lead to targeted immunotherapies.

This review summarizes research on scar formation and inhibition mechanisms, discussing emerging therapies like gene therapy and stem cell treatments, but notes ongoing challenges for clinical application, including treatment personalization and outcome sustainability.

This review article explores the potential systemic nature of alopecia areata, highlighting the association with ocular abnormalities and suggesting that shared pathogenic pathways may lead to eye symptoms occurring at younger ages than usual.

This study highlights the genetic complexities in alopecia areata, emphasizing the role of microRNAs and their association with other immune-related diseases, which could inform targeted treatment strategies.

This paper discusses the balance between target tissue destruction and recovery rates in autoimmune diseases, proposing that high recovery rates are crucial for remitting-relapsing patterns, while exercise might not be neuroprotective in secondary progressive multiple sclerosis.

This study reviews the role of hair follicles in the development, symptoms, and treatment options for vitiligo and alopecia areata, aiming to enhance understanding of their involvement in these autoimmune conditions and explore potential therapies.

This review explores the cellular mechanisms of tissue repair and discusses how advancements in understanding wound pathology could lead to the development of more effective therapies for chronic, non-healing wounds, which are prevalent among individuals with diabetes and aging.

This review explores the diverse physiological roles of the vitamin D endocrine system, discussing current research on receptor structure, transcription details, murine models, and alternative receptors, but reports no new findings.

This study examined recent findings on the role of host-microbiome interactions in acne, highlighting that the skin's microbiome composition differs between acne-affected and healthy individuals and discussing emerging microbiome-based treatments.

This review discusses the autoimmune nature of alopecia areata, potential therapeutic targets, and highlights the need for further studies on immunomodulatory treatments and genetic factors, but it reports no new clinical results.

This narrative review discusses advancements in the understanding and treatment of dermatitis herpetiformis as a manifestation of celiac disease and reports no new research results.

This review discusses recurrent implantation failure (RIF) in IVF, noting the lack of standard definitions or treatment protocols, and emphasizes the need for individualized treatment and further research.

This review discusses the pathogenesis of alopecia areata, highlighting the role of immune privilege collapse in hair follicles but reports no clinical results.

This review explores the hair follicle microbiome's interaction with the immune system, discussing its potential clinical implications for scalp health and disease but reports no new clinical results.

This review discusses progress in targeted therapies for vitiligo, focusing on Janus kinase inhibitors and the potential of mesenchymal stem cells, but reports no new clinical results.

This review discusses the interplay between hormonal and immune systems in hair follicles and reports no new results, highlighting the need for further research on their role in skin biology and alopecia areata.

This review explores the role of macrophage subsets in adult cutaneous wound healing and emphasizes their potential for therapeutic targeting, but reports no new experimental results.

Healthy mitochondria in skin cells are essential for proper hair growth and skin cell interaction in mice.

This review article highlights recent progress and challenges in stem cell transplantation for regenerative medicine, emphasizing its potential in tissue repair for conditions like bone and cartilage injuries, neurological disorders, and blood diseases, while stressing the importance of overcoming current obstacles for future advancements.

This review discusses recent advances in scarless wound healing research, focusing on the roles of mechanobiology and immunology, and reports no new clinical results; the authors highlight the potential of next-generation human skin equivalents in understanding these mechanisms.

The Dfl mutation in mice causes poor sebaceous gland function and complete hair loss.

This review discusses the regulatory roles of type 2 alarmin cytokines in skin immunity, focusing on their implications in host defense, chronic inflammation, and cancer, but reports no new clinical results.

This review discusses neuroimmune communication in skin disorders and peripheral neuropathic pain, highlighting the complex interactions between sensory neurons and immune cells; it reports no new clinical results but suggests potential future therapies.

This review discusses the regulatory roles of lysophospholipids like LPA and S1P in diseases such as fibrosis, neuropathic pain, and cancer, but reports no new clinical results.

This review highlights the need for a deeper understanding of the genetic mechanisms in alopecia areata to develop evidence-based treatments, but it provides no new experimental results.

This review discusses the unique advantages and challenges of microneedle arrays for vaccine and immunotherapy delivery but reports no new clinical results.