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New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

The document concludes that systemic therapy is becoming more important in treating head and neck cancer, with new treatments showing promise.

New treatments like nanotechnology show promise in improving skin cancer therapy.

Higher GPER-1 levels are linked to more severe and shorter-duration androgenetic alopecia, suggesting GPER-1 as a potential treatment target.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

A substance called poly(I:C) increases a protein called carbonic anhydrase II in skin cells, which might help with skin defense and healing.

Leptin helps start the growth phase of hair.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.

Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.

Tirzepatide improved symptoms and hair regrowth in a man with folliculitis decalvans.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Cannabinoids may help treat various skin conditions.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

The drug BAY 1158061 is safe, well-tolerated, and shows potential for treating diseases related to prolactin.

Restoring hair bulb immune privilege is crucial for managing alopecia areata.

A child with low platelets and anemia was later found to have lupus.

The vitamin D receptor helps maintain hair and bone health even without binding vitamin D.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.

Hair graying is influenced by factors like nerves, fat cells, and immune cells, not just hair follicles.

Oxytocin receptors are found in skin cells near touch and pain neurons.

Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.

The document concludes that eyelash trichomegaly, which is the abnormal growth of eyelashes, can be present from birth, caused by diseases, or result from certain medications.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.