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Tofacitinib citrate is effective for moderate-to-severe chronic plaque psoriasis but has safety concerns at higher doses.

Understanding and tracking our body's natural daily rhythms could help improve heart health.

Skin varies in thickness, color, and features due to complex genetic and cellular processes.

Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.

A man's gray hair got darker and thicker after using a psoriasis drug.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

Zinc helps reduce the severity of depression.

The reviewers found the manuscript on inflammation's role in cancer stem cells to be relevant but suggested it needs clarity, more background information, discussion on immune cells' role in tumors, updated references, and grammar corrections.

The reviewers suggest clarifying the abstract, adding background on inflammation's effect on stem cells and cancer, discussing immune cells' role in tumors, and considering inflammation's potential to reduce cancer growth.

Reviewers suggest clarifying the abstract, adding background on inflammation's effect on cancer, discussing immune cell roles, including counter studies, and correcting grammar.

Different genes and pathways are active in yak skin and hair cells, affecting hair growth and immune responses.

Omics techniques are needed to understand the scalp microbiome's role in alopecia areata for new treatments.

NSG mice had the most mites, and genetic factors affect immune response and susceptibility.

The conclusion is that having both Frontal Fibrosing Alopecia and Discoid Lupus Erythematosus may suggest a shared immune response in certain people, and a mix of antimalarial drugs and 5-alfa-reductase inhibitors is recommended for treatment.

TLR3 activation helps improve skin and hair follicle healing in mice.

New findings suggest targeting IL-23 could treat psoriasis, skin cells can adapt to new roles, direct conversion of skin cells to blood cells may aid cell therapy, removing certain tumor cells could boost cancer immunotherapy, and melanoma may have many tumorigenic cells, not just cancer stem cells.

Hair follicle biology advancements may lead to better hair growth disorder treatments.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.

The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.