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Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.

The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.

A patient with Alopecia Areata had complete hair regrowth after using the drug baricitinib.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Dexamethasone speeds up hair loss in mice, while cyclosporin A slows it down.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

EGF makes hair follicles grow longer but stops hair production.

Lichen planopilaris is a chronic, scarring hair loss condition with no definitive cure, requiring accurate diagnosis and treatment to manage symptoms.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

The Lexington LaserComb helped regrow hair in mice with a condition similar to human hair loss.

Oral tofacitinib can significantly improve recalcitrant lichen planopilaris.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Hair grays due to oxidative stress and fewer functioning melanocytes.

The conclusion is that hair growth can be improved by activating hair cycles, changing the surrounding environment, healing wounds to create new hair follicles, and using stem cell technology.

Antioxidants may help fight oxidative stress linked to autoimmune skin diseases.

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

FFA's causes may include environmental triggers and genetic factors.

The document concludes that alopecia areata is an autoimmune disease without a definitive cure, but treatments like corticosteroids are commonly used.

Baricitinib is effective and safe for treating severe alopecia areata.