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Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.

Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Understanding different types of skin cells, especially fibroblasts, can lead to better treatments for wound healing and less scarring.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Alopecia areata is caused by immune system attacks on hair follicles, often triggered by viral infections.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.

Advanced human skin models improve drug development and could replace animal testing.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.