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Polymeric microneedles offer a less invasive, long-lasting drug delivery method that improves patient compliance and reduces side effects.

Docetaxel often causes hair loss, with limited effective treatments and no cure for permanent hair loss.

Topical minoxidil is the best-supported treatment for female hair loss, but personalized plans are needed.

Dietary lipids affect inflammation and are crucial for normal cell function and immune health.

POMC-derived peptides are important for skin functions like immune response and stress management.

Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.

Dandruff might be caused by changes in how hair follicles naturally release oils and an immune response to this imbalance.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Leptin, a hormone from fat cells, affects immune responses and can influence skin diseases and hair growth.

Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.

Eating plant-based anti-inflammatories and antioxidants may help manage long-term COVID-19 health issues.

Advanced human skin models improve drug development and could replace animal testing.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Selective breeding can enhance immunity in dairy cattle.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.

Non-immune factors play a significant role in alopecia areata.

Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.

Hair graying is influenced by factors like nerves, fat cells, and immune cells, not just hair follicles.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

Alopecia areata causes hair loss due to an immune attack on hair follicles, influenced by genetics and environment.

sPLA2-IIE is crucial for normal hair follicle structure and skin health.

Pure carbon nanotubes are safe for mice, but impure ones cause immune issues and hair loss.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.

The document concludes that eyelash trichomegaly, which is the abnormal growth of eyelashes, can be present from birth, caused by diseases, or result from certain medications.

Gefitinib and Sasam-Kyeongokgo together significantly reduce cancer growth and improve immune response in mice.