April 2024 in “Expert opinion on investigational drugs” JAK inhibitors are safe and effective for treating moderate-to-severe alopecia areata.
9 citations,
August 2014 in “Journal of The American Academy of Dermatology” Hormonal imbalances may play a role in frontal fibrosing alopecia, and antiandrogenic drugs combined with steroids are currently the most effective treatment.
6 citations,
December 2013 in “Journal of Investigative Dermatology Symposium Proceedings” Alopecia areata involves complex immune and genetic factors, with potential treatment targets identified, but more research is needed.
5 citations,
September 1989 in “Journal of The American Academy of Dermatology” Talc in street cocaine can cause immune-reactive skin nodules where injected.
2 citations,
January 2019 The document concludes that autoimmune skin disorders are treated with corticosteroids and immunosuppressive drugs.
September 2023 in “Medicine” The research suggests immune system changes and specific gene expression may contribute to male hair loss, proposing potential new treatments.
March 2018 in “Suez Canal University Medical Journal” New drugs targeting the JAK-STAT pathway show promise for treating inflammatory skin diseases.
114 citations,
January 2007 in “Drug Safety” Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.
70 citations,
February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
46 citations,
January 1996 in “Journal of The American Academy of Dermatology” People with late-stage HIV-1 often experience a specific type of hair loss linked to multiple factors, including nutritional issues and immune responses.
43 citations,
July 2017 in “International journal of pharmaceutics” Using β-cyclodextrin derivatives improves the solubility and bioavailability of steroidal drugs.
26 citations,
March 2014 in “Rheumatology” Some drugs used to treat inflammation may cause hair loss.
9 citations,
December 2020 in “Dermatologic Therapy” Certain drugs are effective for skin conditions like psoriasis, vitiligo, and hair loss.
7 citations,
June 2015 in “Cutaneous and Ocular Toxicology” Some drugs can cause skin reactions, which may improve when the drug is stopped, and rapid diagnosis and stopping the drug is crucial.
4 citations,
January 2012 in “Chemical Immunology” Some drugs, especially biologics, can cause skin reactions that look like other skin diseases, and stopping the drug usually helps clear up these reactions.
1 citations,
December 2023 in “Nanomaterials” Combining specific nanoparticles with immune therapy significantly improves cancer treatment.
1 citations,
August 2020 in “IntechOpen eBooks” Old drugs like finasteride and spironolactone are being successfully used for hair loss and skin conditions, and many other drugs show promise for new uses in dermatology.
October 2023 in “Microorganisms” Nirmatrelvir/Ritonavir treatment may lead to a weaker immune response to COVID-19, but doesn't affect the chance of rebound.
January 2023 in “Rossijskij žurnal kožnyh i veneričeskih boleznej” New treatments for child hair loss due to immune issues are effective but not yet officially approved.
June 2019 in “Advanced medical journal” Cancer drugs often cause temporary hair, skin, nail, and mouth issues.
November 2022 in “Annals of Translational Medicine” Immune activities and specific genes are important in male pattern baldness.
191 citations,
May 2018 in “British journal of dermatology/British journal of dermatology, Supplement” Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.
179 citations,
October 2018 in “American Journal of Clinical Dermatology” Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.
144 citations,
September 2006 in “Clinics in Dermatology” Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.
139 citations,
December 2020 in “Cell Stem Cell” Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
134 citations,
July 2020 in “Experimental dermatology” Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.
125 citations,
September 2019 in “Journal of Clinical Immunology” Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.
125 citations,
December 2016 in “Molecules” Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.
51 citations,
May 2013 in “The Journal of Steroid Biochemistry and Molecular Biology” Certain drugs that block specific enzymes can help treat prostate diseases.
44 citations,
November 1998 in “Australasian Journal of Dermatology” Accurate diagnosis is key for treating different kinds of hair loss, and immune response variations may affect the condition and treatment results.