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Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.

Pregnancy can cause specific skin conditions that need correct diagnosis and treatment to protect both mother and baby.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.

Platelet-rich treatments can help improve wound healing and tissue repair.

Acne is caused by multiple factors including oil production, bacteria, inflammation, and possibly diet and environment.

CD8+ T cells play a key role in graft-versus-host disease in certain mice models.

Zinc helps reduce the severity of depression.

The document concludes that effective acne treatment requires a personalized combination of therapies and long-term commitment, with retinoids being important for maintenance.

Type-2 immunity may influence skin diseases and could be targeted for treatment.

Good nutrition and essential trace elements like zinc, selenium, and iron are important for a strong immune system and reducing COVID-19 severity.

The reviewers found the manuscript on inflammation's role in cancer stem cells to be relevant but suggested it needs clarity, more background information, discussion on immune cells' role in tumors, updated references, and grammar corrections.

The reviewers suggest clarifying the abstract, adding background on inflammation's effect on stem cells and cancer, discussing immune cells' role in tumors, and considering inflammation's potential to reduce cancer growth.

Reviewers suggest clarifying the abstract, adding background on inflammation's effect on cancer, discussing immune cell roles, including counter studies, and correcting grammar.

Certain genes and nutrients like vitamin D, zinc, and omega fatty acids affect COVID-19 severity and infection risk.

Discoid Lupus Erythematosus often causes scarring hair loss, is influenced by genetics and environment, and requires early treatment to prevent worsening.

The document concludes that managing skin conditions during pregnancy is important and requires specialized care.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

New treatments for Alopecia Areata show promise but need to be more effective and affordable.

Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.