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Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.

Androgens prevent hair growth by changing Wnt signals in cells.

The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.

Wnt5a may contribute to psoriasis by reducing skin cell growth, blocking skin cell maturation, and increasing inflammation.

Thymic transplantation normalized some T-cells but not others, maintaining immune function.

Inflammation helps stem cells repair tissue by directing their behavior.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Embryonic and adult stem cells are valuable for improving skin grafts and cell therapy.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Fat cells are important for tissue repair and stem cell support in various body parts.

Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.

Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.

The document concludes that pregnancy and cancer share immune evasion tactics, but more research is needed before using checkpoint blockade immunotherapy in pregnant cancer patients to avoid harm to the placenta.

Laminin 332 is essential for normal skin cell behavior and structure.

Targeting the protein Caveolin-1 might help treat a type of scarring hair loss called Frontal Fibrosing Alopecia.

Different types of fibroblasts play specific roles in wound healing and cancer, which could help improve treatments.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Wnt signaling is crucial for skin wound healing and reducing scars.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.

B2m-free HLA variants may be a new class of HLA important in immune responses and diseases.

Blocking a specific immune cell signal can trigger hair growth.

Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

Intermediate filaments are crucial for cell differentiation and stem cell function.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.