research Melatonin Membrane Receptors in Peripheral Tissues: Distribution and Functions
Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
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research Getting Under the Skin: What Is the Potential of the Transfollicular Route in Drug Delivery?
The transfollicular route shows promise for noninvasive, targeted drug delivery but needs more research.
research Selective Expansion of Tregs Using the IL-2 Cytokine Antibody Complex Does Not Reverse Established Alopecia Areata in C3H/HeJ Mice
Increasing Treg cells in the skin does not cure hair loss from alopecia areata in mice.
research Topical Janus Kinase Inhibitors: A Review of Applications in Dermatology
Topical JAK inhibitors may help treat some skin conditions but need more research.
research Rosemary Extracts Containing Carnosic Acid and Carnosol Are Potent Quorum Sensing Inhibitors of Staphylococcus Aureus Virulence
Rosemary extracts with carnosic acid and carnosol can reduce the harmfulness of Staphylococcus aureus without stopping its growth.
research Genetically-Manipulated Adult Stem Cells as Therapeutic Agents and Gene Delivery Vehicles for Wound Repair and Regeneration
Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.
research Major Improvement in Wound Healing Through Pharmacologic Mobilization of Stem Cells in Severely Diabetic Rats
A new therapy sped up wound healing and reduced scarring in diabetic rats.
research Efficacy and Safety of Different JAK Inhibitors in the Treatment of Alopecia Areata: A Network Meta-Analysis
Oral baricitinib and ruxolitinib are effective and safe for treating alopecia areata.
research In-Silico Cardiac Aging Regulatory Model Including MicroRNA Post-Transcriptional Regulation
Researchers created a model to understand heart aging, highlighting the role of microRNAs and identifying key genes and pathways involved.
research Androgenetic Alopecia: Causes, Treatments, and Genetic Factors
Heredity and hormones cause common hair loss, and topical minoxidil is the first recommended treatment.
research A Computationally Inferred Regulatory Heart Aging Model Including Post-Transcriptional Regulations
Researchers created a model to understand heart aging, highlighting key genes and pathways, and suggesting miR-208a as a potential heart attack biomarker.
research Novel Advances of Histone Modification in Inflammatory Skin Diseases and Related Treatment Methods
Histone modification is key in treating chronic inflammatory skin diseases.
research II Nanosciences and Nanotechnology Biomedicals Symposium - Proceedings
Nanotechnology shows promise for better drug delivery and cancer treatment.
research Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib
A patient with Alopecia Areata had complete hair regrowth after using the drug baricitinib.
research The Endocannabinoid System of the Skin: A Potential Approach for the Treatment of Skin Disorders
Targeting the skin's endocannabinoid system could help treat skin disorders.
research Drug Repurposing: Hypothesis, Molecular Aspects, and Therapeutic Applications
Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
research The Basic Science of Hair Biology
Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.
research Effect of an Oral Probiotic Formula on Scalp and Facial Skin Condition, Glucose, and Lipid Metabolism
Taking a probiotic supplement twice a day improved hair growth, skin hydration, and metabolic health in adults at risk of metabolic syndrome.
research Enhancing Hair Regeneration: Recent Progress in Tailoring Nano-Structured Lipid Carriers Through Surface Modification Strategies
Surface-modified nanostructured lipid carriers can improve hair growth treatments.
research Androgen Excess: A Hallmark of Polycystic Ovary Syndrome
Excess androgens may cause PCOS, not just be a symptom.
research Drug Armamentarium for Alopecia Areata
No cure exists for alopecia areata, and treatments are personalized.
research Premature Aging Syndromes: From Patients to Mechanism
Studying premature aging syndromes helps understand human aging and suggests potential treatments.
research Cannabinoid Compounds as a Pharmacotherapeutic Option for the Treatment of Non-Cancer Skin Diseases
Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.
research Platelet-Derived Bio-Products: Classification Update, Applications, Concerns, and New Perspectives
Platelet-derived bio-products help in wound healing and tissue regeneration but lack standardized methods, and their use in medicine is growing.
research Revisiting the Role of Melatonin in Human Melanocyte Physiology: A Skin Context Perspective
Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.
research Enhancing Skin Anti-Aging Through Healthy Lifestyle Factors
Healthy lifestyle changes can significantly improve skin health as you age.
research Optimization of Lipid-Based Nanoformulation for Cutaneous Targeting: Niosomes as Potential Candidates
Niosomes are the most effective at delivering drugs to the skin with minimal absorption into the body.
research Use of Exosomes for Cosmetics Applications
The review article explores the potential of exosomes in cosmetics and regenerative medicine, focusing on their roles in skin rejuvenation, wound healing, and tissue repair. Exosomes, nanosized extracellular vesicles, deliver growth factors and bioactive molecules, offering non-invasive alternatives to traditional treatments. Despite promising applications, challenges such as regulatory barriers, standardization issues, and a lack of clinical validation persist. The study reviewed 37,972 studies, highlighting significant interest in exosome research, particularly in wound healing. Exosomes show promise in enhancing skin hydration, elasticity, and pigmentation regulation, but further research and clinical trials are needed to validate their safety, efficacy, and feasibility in dermatology and plastic surgery.
research Repurposing DPP4-Inhibition to Improve Hair Follicle Activation and Regeneration
Blocking DPP4 can potentially speed up hair growth and regeneration, especially after injury or in cases of hair loss.
research Matrisomal Components Involved in Regenerative Wound Healing in Axolotl and Acomys: Implications for Biomaterial Development
Certain genes are more active during wound healing in axolotl and Acomys, which could help develop materials that improve human wound healing and regeneration.