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Using existing drugs for new purposes could be a cost-effective way to treat chest pain and non-clogged heart arteries, with some drugs for lung blood pressure showing promise but needing more testing.

Hair loss can be caused by stress, aging, and harmful substances that create an imbalance in the body's natural processes.

The vitamin D receptor helps regulate skin and hair health independently of its usual vitamin D ligand.

Hair follicle stem cell transplants can reverse liver cirrhosis by blocking harmful cell activation.

Creating fully functional artificial skin for chronic wounds is still very challenging.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.

RT1640 treatment reverses gray hair and promotes hair growth in mice.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Understanding how EDC genes are regulated can help develop better drugs for skin diseases.

VDUP1 is found in skin and hair follicles, interacts with sciellin, and may help regulate skin cell differentiation.

SV40 T antigen in hair follicles causes abnormal hair and health issues in mice.

Testosterone can both promote hair growth and cause baldness by affecting hair growth signals.

Topical spironolactone may help treat ocular graft-versus-host disease with minimal side effects.

Marine-derived ingredients show potential for hair health but need more human trials to confirm effectiveness.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Fullerenes show potential in skin care but need more safety research.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Human hair follicles can regenerate after removal, but with low success rate.

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.