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The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

New topical antifungals and delivery systems are improving treatment for fungal skin infections, but patient education and prevention are key.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

Improving skin barrier and using antifungal treatments can help manage dandruff.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

The document concludes that specific itchy skin diseases during pregnancy have varying fetal risks and treatments, including corticosteroids and other medications.

Antioxidants can benefit skin health but should be used carefully to avoid negative effects.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

A weight loss program with a special fast helped patients lose an average of 41-47 pounds and improved their health, but maintaining the weight loss was challenging.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

Imiquimod 5% cream reduced equine sarcoids in most cases.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

The document concludes that careful evaluation is key to diagnose and treat women with hair loss, with tests for thyroid, iron, and hormones as needed.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

The cause of Frontal Fibrosing Alopecia is unclear, diagnosis involves clinical evaluation and various treatments exist, but their effectiveness is uncertain.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

The flexible fixed-sequence testing method allows for more effective evaluation of multiple goals in a clinical trial while controlling the risk of false positives.

The document concludes that more research is needed to understand how to treat muscle pain with drugs.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

Manatee whiskers are specially adapted for touch in water.

A systematic approach is crucial for managing hair loss in women.

Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.

Foxi3 expression in developing teeth and hair is controlled by the ectodysplasin pathway.

Germ-free rats need biotin for growth and have different vitamin metabolism compared to regular rats.