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The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

A woman with breast cancer developed a rare condition causing excessive fine hair growth on her face and body.

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

A gene in Arabidopsis thaliana, AtPRPL1, affects root hair length but not cell wall composition.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

Finasteride reduces prostate bleeding by affecting blood vessel growth.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.

Measuring reproductive hormones in brown bear hair could help identify their sex and reproductive state, but better collection methods or lab techniques are needed.

Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.

Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.

Pannexin 3 is important for bone formation and the development of bone cells.

Extramammary Paget disease can spread deeply into tissues, reaching up to 3.6 mm.

The document concludes that recognizing oral lesions is important for diagnosing syphilis.

Certain proteins are essential for the growth of root hairs in barley.

Thymic transplantation normalized some T-cells but not others, maintaining immune function.

Apple-derived procyanidin B-2 can safely promote hair growth in men.

Platelet-Rich Plasma (PRP) therapy can promote hair growth and improve facial aesthetics, including reducing acne scars and facial burns, and it works best with three initial monthly injections.

The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.

LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.

Continuous light exposure in rats leads to PCOS-like symptoms and suggests sleep habits might affect the disorder's development.

Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

Flutamide combined with an LHRH agonist effectively inhibits prostate growth, suggesting it could treat prostate cancer.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.