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The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Terbinafine and itraconazole are more effective against Microsporum canis than fluconazole and griseofulvin.

Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

Fibromodulin treatment helps reduce scarring and improves wound healing by making it more like fetal healing.

People with HIV and low T cell counts have more hair and scalp problems.

Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.

Enzyme purified and characterized for minoxidil sulphation in rat liver.

Ketoconazole shampoo with finasteride improves hair density in men with hair loss.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Early diagnosis and effective treatment of kerion Celsi prevent scarring and permanent hair loss.

Researchers found an RNA transcript that might help control a growth factor linked to tumor development.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

The new nanocomposite films are stronger, protect against UV, speed up wound healing, and are antibacterial without being toxic.

The composition with carnitine, thioctic acid, and saw palmetto extract may effectively reduce inflammation in hair follicle cells.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.

The study concludes that certain domains in Clostridium histolyticum enzymes are structurally unique, bind calcium to become more stable, and play distinct roles in breaking down collagen, with potential applications in medicine and drug delivery.

Itraconazole helps improve tough skin infections but may not prevent them from coming back.

RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.

The new palladium catalyst is effective and reusable for making pharmaceutical ingredients.

The document explains various skin conditions in cats and how to diagnose and treat them.

New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.

Some oral medications may help treat central serous chorioretinopathy, especially eplerenone, but more research is needed.