264 citations
,
January 2008 in “Journal of biomedical optics” This study found that ZnO nanoparticles in topical skin products do not penetrate beyond the outer skin layers in humans, suggesting minimal safety concerns for subdermal absorption.
36 citations
,
July 2004 in “Apmis” This review describes three mouse models using fluorescent proteins to image tumor angiogenesis in real-time, but reports no new clinical results.
30 citations
,
June 2017 in “Talanta” This review discusses the critical parameters for MALDI IMS sample preparation in skin analysis and highlights its applications in wound healing, neoplasia, and infection research, but reports no new clinical results.
21 citations
,
October 2011 in “PloS one” In this study, researchers identified three molecules in hair that varied with age, suggesting potential markers for aging and targets for cosmetic products.
21 citations
,
July 2004 in “Apmis” This review describes the development of three mouse models using fluorescent proteins to visualize and study angiogenesis in tumors, particularly detailing interactions between tumor cells and the surrounding stroma.
16 citations
,
May 2017 in “Journal of Clinical Ultrasound” This report describes the sonographic characteristics of a proliferating trichilemmal tumor in the subungual region, identifying it as a heterogeneous mass with echogenic foci, potentially representing keratin and cholesterol.
5 citations
,
March 2017 in “Immunology and Cell Biology” This review discusses recent advances in biomedical imaging for cancer research, particularly highlighting improved imaging tools for studying solid tissue malignancies, and reports no new clinical results.
4 citations
,
March 2018 in “Journal of labelled compounds & radiopharmaceuticals” In this study, researchers developed a new prostate cancer imaging agent, a [99m Tc]tricarbonyl complex derived from finasteride, which demonstrated high radiochemical purity and significant uptake in the prostate of a rat model, suggesting its potential for noninvasive prostate cancer imaging.
2 citations
,
May 2023 in “Experimental dermatology” In this study, researchers used advanced four-dimensional optical imaging techniques to observe changes in skin afflicted with acne, finding increased epidermal thickness, keratinized hair follicles, inflammation, and aggregated blood flow, helping to distinguish between inflammation and reparative phases of acne progression.
1 citations
,
August 2025 in “Medicina” This review discusses the evolution and potential of non-invasive imaging techniques for diagnosing scalp diseases, highlighting their advantages and limitations compared to trichoscopy and scalp biopsy, the current diagnostic standards.
1 citations
,
May 2025 in “The Journal of Rheumatology” This case report highlights the challenge of distinguishing between neuropsychiatric lupus and rituximab-associated progressive multifocal leukoencephalopathy in systemic lupus erythematosus patients, emphasizing the importance of early recognition and careful management.
January 2026 in “The Operating Room Global Journal” This review found that image-guided techniques in regenerative aesthetic procedures may enhance accuracy and patient outcomes compared to traditional methods, but more high-quality randomized trials are needed to establish standardized protocols.
This review discusses recent advances in noninvasive hair imaging technologies, such as global photography, trichoscopy, reflectance confocal microscopy, and optical coherence tomography, highlighting their potential to improve hair diagnostics and treatment monitoring, while also outlining their clinical applications and limitations.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that Imaging Mass Cytometry effectively visualizes multiple biomarkers in alopecia areata, enhancing analysis of immune cell and tissue interactions in hair pathology.
January 2017 in “Nihon Keshouhin Gijutsushakaishi/Journal of S C C./Nihon Keshouhin Gijutsushakai kaishi” This study found that hair damage from sunlight and chemical processes like perms and bleaching varies in internal microstructure changes, suggesting that protective techniques should be tailored to the type of chemical treatment used.
305 citations
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June 2012 in “Nature” This study reports that hair regeneration in live mice involves spatially regulated stem cell divisions and requires mesenchymal interactions, observed in real-time using a novel non-invasive imaging method.
56 citations
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June 2015 in “Nature Protocols” This protocol describes using two-photon laser-scanning microscopy to study hair regeneration in live mice, offering detailed imaging capabilities for observing hair follicle stem cell behavior and manipulating cellular populations.
42 citations
,
January 2011 in “Journal of Biomedical Optics” This study demonstrates that spatially resolved IR and Raman imaging can effectively reveal the molecular structure and composition of untreated human hair, providing insights into its chemistry and structural integrity.
37 citations
,
July 2016 in “Current Opinion in Cell Biology” This review summarizes recent discoveries about how tissue-resident stem cells interact with their environments during normal conditions and after injury, without reporting new results.
28 citations
,
March 2019 in “Cellular Microbiology” This review discusses the advancements enabled by intravital microscopy in understanding host-parasite interactions in living animals and reports no new clinical results.
23 citations
,
March 2023 in “eLife” This study reveals that epidermal stem cell differentiation in mice involves dynamic transcriptional changes, with Keratin-10 transcription preceding gradual chromatin compaction shifts associated with differentiation.
19 citations
,
January 2013 in “Frontiers in Neuroanatomy” This study demonstrates a method using intravital imaging to observe sensory hair-cell development and regeneration in zebrafish, which may facilitate assays for drug discovery related to aural function preservation.
19 citations
,
July 2009 in “Clinical and Experimental Dermatology” This article discusses how the balding scalp's exposure to UV and near-infrared light may accelerate aging, with changes detectable under ultraviolet light; it presents no new clinical findings.
17 citations
,
December 2014 in “Cell Stem Cell” This discussion explores advances in intravital imaging for visualizing stem cells, highlighting key discoveries and potential future developments; it reports no new experimental results.
14 citations
,
January 2018 in “Scientific reports” This study demonstrated that bioluminescence imaging of NG2+ cells in transgenic rats allows in vivo monitoring of hair follicle cycles to study hair growth and follicle regeneration.
14 citations
,
July 2007 in “International Journal of Cosmetic Science” This study found that a new 3D image analysis method from SEM images enables quick and accurate measurement of cuticle scale heights in hair fibers.
12 citations
,
July 2017 in “Journal of cosmetic dermatology” This study suggests that infrared thermography may be a useful noninvasive tool for diagnosing active phases of frontal fibrosing alopecia when combined with dermoscopy.
12 citations
,
September 2007 in “Wound repair and regeneration” This study found that in vivo bioluminescence can track Smad2/3-dependent TGF-β signaling during the wound healing process in mice, with signaling increasing after healing rather than immediately post-wounding.
11 citations
,
October 2020 in “Sensors” This study found that photoacoustic imaging can effectively measure follicle density and angles, even when follicles are not visible to the eye, providing a promising alternative to traditional photographic examination.
9 citations
,
February 2024 in “Indian Dermatology Online Journal” This study discusses the potential of advanced imaging technologies in dermatology to improve diagnostic accuracy and reduce the need for invasive procedures like biopsies, while noting significant barriers in adoption and accessibility in India due to costs and infrastructure constraints.