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Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

2% topical minoxidil effectively treats female hair loss with minimal side effects.

Memantine may slightly improve memory in people with Down syndrome, but more research is needed.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.

Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.

Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.

Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

We don't fully understand how sunlight damages different types of hair.

Doctors need to be better prepared to assess and treat obesity in patients.

PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.

Technique creates 3D cell spheroids for hair-follicle regeneration.

Improving insulin sensitivity and weight loss can help manage polycystic ovary syndrome (PCOS).

Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.

PCOS is often linked to insulin resistance and obesity, and weight loss can improve symptoms.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

The new micelle formulation delivers acne treatment more effectively and safely than current gels.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Tattooing helps treat skin conditions, reconstruct nipple-areola, mark radiation fields, and locate lesions.

Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.

The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

Keratins are important for skin cell health and their problems can cause diseases.

Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Treating cystoid macular oedema in uveitis is difficult and risky.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.