September 2017 in “Journal of Investigative Dermatology” QMSI effectively maps and quantifies drug distribution in skin tissues.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that Quantitative Mass Spectrometry Imaging offers precise localization and quantification of active compounds in skin tissues, demonstrating benefits over traditional LC-MS in drug penetration studies.
4 citations
,
March 2018 in “Journal of labelled compounds & radiopharmaceuticals” In this study, researchers developed a new prostate cancer imaging agent, a [99m Tc]tricarbonyl complex derived from finasteride, which demonstrated high radiochemical purity and significant uptake in the prostate of a rat model, suggesting its potential for noninvasive prostate cancer imaging.
14 citations
,
November 2019 in “Materials” This study found that nanodiamonds of various sizes can penetrate different layers of murine skin in vitro, reaching hair follicle niches, and may be suitable for multimodal imaging applications.
5 citations
,
November 2003 in “PubMed” This study found that chemical and photochemical oxidative processes modify the main classes of proteins in hair, confirmed through microspectrophotometric, fluorescence microscopy, and electrophoretic methods.
84 citations
,
September 2014 in “European journal of endocrinology” This review examines the causes and characteristics of androgen excess in postmenopausal women, but reports no new clinical results; the authors emphasize challenges in diagnosis and potential long-term health impacts.
27 citations
,
July 2018 in “Journal of optometry” This review discusses the biology, pathophysiology, and management of eyelash anomalies, highlighting the need for more research into eyelash mechanisms and care, and reports no new clinical results.
2 citations
,
October 2023 in “Dermatology practical & conceptual” This systematic review evaluated 60 studies on trichoscopy in hair and scalp disorders, revealing gaps in accounting for variables like disease stage or hair texture, and underscoring a need for more comprehensive analyses to fully understand trichoscopic patterns.
This review discusses the advancements and applications of multiphoton microscopy in dermatology, including its role in imaging skin disease and drug transport, and reports no new clinical results.
36 citations
,
February 1998 in “Journal of Anatomy” This study used fibre optic confocal imaging to visualize subsurface structures in live mouse skin, revealing cellular details and blood vessel networks that dynamic events could be studied in vivo.
2 citations
,
September 2024 in “Lasers in Surgery and Medicine” This study concluded that noninvasive imaging techniques offer potential benefits in managing scalp conditions by potentially reducing the need for biopsies and minimizing patient morbidity, each technique having unique advantages and limitations for specific conditions.
August 2019 in “Journal of Investigative Dermatology” This study found that tight junctions extend to the most superficial layer of the stratum granulosum in human skin, challenging previous claims of their limited presence in the epidermis.
April 2017 in “Journal of Investigative Dermatology” This study found that retinoic acid and a retinol complex formulation showed different permeation and compound localization in a skin equivalent model, with unique lipid changes observed with only the retinol formulation.
5 citations
,
March 2017 in “Laser Physics Letters” This review discusses the role of scalp imaging techniques in trichology for researching drug delivery and toxicology, without presenting new clinical results.
January 2026 in “The Operating Room Global Journal” This review found that image-guided techniques in regenerative aesthetic procedures may enhance accuracy and patient outcomes compared to traditional methods, but more high-quality randomized trials are needed to establish standardized protocols.
May 2024 in “Indian journal of pharmacy and pharmacology” This in-vitro study reported that a luliconazole-based formulation improved hair cuticle integrity and was more effective than ketoconazole in repairing damaged hair after 5 and 10 washes, with sensory analysis supporting these results. Further human studies are needed to confirm its clinical effects.
30 citations
,
June 2017 in “Talanta” This review discusses the critical parameters for MALDI IMS sample preparation in skin analysis and highlights its applications in wound healing, neoplasia, and infection research, but reports no new clinical results.
19 citations
,
January 2013 in “Frontiers in Neuroanatomy” This study demonstrates a method using intravital imaging to observe sensory hair-cell development and regeneration in zebrafish, which may facilitate assays for drug discovery related to aural function preservation.
18 citations
,
April 2001 in “Bioorganic & Medicinal Chemistry Letters” This study identified the N-(iodopropenyl) derivative 13 as a promising candidate for development as a radioiodinated androgen receptor ligand due to its binding affinity.
12 citations
,
September 2007 in “Wound repair and regeneration” This study found that in vivo bioluminescence can track Smad2/3-dependent TGF-β signaling during the wound healing process in mice, with signaling increasing after healing rather than immediately post-wounding.
4 citations
,
February 2018 in “Journal of Investigative Dermatology” This study suggests that thermal imaging may aid in diagnosing cellulitis, potentially improving patient care, although its applicability to certain cases requires further investigation.
3 citations
,
November 2013 in “Journal of Stem Cells and Regenerative Medicine” This article suggests that imaging abnormalities in intestinal stem cell compartments could potentially be incorporated into colorectal cancer screening, but provides no new clinical results.
1 citations
,
May 2001 in “Journal of Labelled Compounds and Radiopharmaceuticals” Scientists at the University of Michigan Medical School successfully created a special compound that can be used to improve imaging of prostate cancer.
This review discusses the dynamic behavior of immune cells in skin immune responses using intravital imaging in mice and reports no new clinical results.
16 citations
,
September 2016 in “Experimental Dermatology” This review provides guidance on using two-photon microscopy for real-time and long-term visualization of stem cell activity in live mice skin, focusing on its application in researching skin and stem cell biology.
In this study, researchers developed a method for high-resolution live imaging of leg regeneration in the crustacean Parhyale hawaiensis, which effectively captures the entire process at cellular resolution over 10 days while minimizing photodamage.
A 73-year-old woman's unusual hair loss and growth led to the discovery of a rare condition causing too much testosterone, which improved after her ovaries were removed.
58 citations
,
November 2013 in “Journal of Innovative Optical Health Sciences” This review discusses the development and application of multiphoton microscopy in dermatology, highlighting its advantages and potential future research directions without reporting new clinical results.
March 2005 in “International Journal of Cosmetic Science” This paper discusses the use of Digital Volumetric Imaging with fluorescent dyes to visualize and compare the interior structures of six different virgin hair types, reporting no new clinical results.
3 citations
,
August 2020 in “Journal of The American Academy of Dermatology” This study observed that patients with scalp dysesthesia frequently exhibited cervical spine degenerative changes, which localized predominantly in the lower cervical spine, and reported modest symptom improvement with neuropathic pain medications and physical therapy.