Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review article highlights recent advances in microneedle technology for wound healing and tissue regeneration, discussing various cargo types, structural designs, and fabrication methods, and suggesting guidelines for designing microneedle systems tailored to specific applications.

This study found that Schistosoma mansoni cercariae stimulate epidermal keratinocytes in mice, initiating pro-inflammatory responses and barrier repair mechanisms akin to those in wound healing.

This review discusses the potential of topical nanoemulsions to transform skin cancer treatment by improving drug delivery and minimizing side effects, highlighting their advantages like enhanced skin permeation and controlled release, despite existing challenges.

This study produced a high-coverage genome of the Tyrolean Iceman, revealing no Steppe-related ancestry but significant Anatolian-farmer-related ancestry, and found genetic markers associated with darker skin, male-pattern baldness, type 2 diabetes, and obesity, aligning with observations of his mummified body.

In this study, researchers demonstrated that in a mouse model, the stimulation of mammary tumor growth due to progesterone is primarily caused by its metabolite, 5αP, not progesterone itself.

This study developed a novel method to simultaneously measure finasteride, dutasteride, and related biomarkers in serum, finding that both drugs lowered DHT levels while increasing substrate concentrations.

This study's simulation found that Ascorbyl Tetraisopalmitate penetrates more efficiently through the skin's stratum corneum than via the infundibulum, following different pathways and dynamics in each membrane.

In this study, researchers highlighted the potential of antioxidative nanozymes as a promising treatment for ischemic stroke, due to their stability, cost-effectiveness, and ability to regulate ROS-induced inflammation, positioning them as a noteworthy alternative to natural enzymes like catalase and superoxide dismutase.

This study identified significant changes in the expression of nine proteins in the nucleus accumbens of rats treated with finasteride, suggesting potential novel targets for its neuropsychiatric effects.

This study found that astaxanthin-loaded mucoadhesive patches effectively promoted recovery of oral premalignant lesions in vivo without the side effects seen with clinical tretinoin cream.

This study demonstrated that molecular dynamics simulations of keratin could effectively model the mechanical properties of hair, aligning well with experimental data, especially when conducted in vacuum conditions.

In this study, researchers used advanced techniques to map the early embryonic development of mouse skin, identifying diverse cell populations and uncovering complex interactions essential for skin structure, signaling, and function.

This study found that exposure to certain pesticides may be associated with delayed sexual maturation in adolescent males.

This study found that applying controlled hypobaric stress to the skin significantly improved the in vitro and in vivo penetration of macromolecules, facilitating enhanced drug delivery.

More research is needed to understand hair aging and develop effective treatments.

This review highlights that current in vitro models often fail to replicate the physiological oxygen levels experienced by different skin cell types, which could affect redox states and functions, potentially accelerating skin aging.

This review examines the use of commonly used dermatological drugs like chloroquine, hydroxychloroquine, ivermectin, antiandrogens, and melatonin in COVID-19 treatment, but reports no new clinical findings.

This study found that a hydro-alcoholic extract of Roselle petals may reduce free radical production during UV-induced photodecomposition of antibiotics, potentially offering protective benefits for patients using similar topical antibiotics.

In this study, complete recovery from folliculitis dissecans was observed after intradermal botulinum toxin A injections, with the effect attributed to the host response rather than direct bacterial action.

This review discusses various microneedle technologies for long-acting drug delivery, highlighting design considerations and challenges in bringing these minimally invasive devices to market, but it reports no new clinical results.

In this study, researchers developed gellan gum hydrogels functionalized with biomimetic peptides that create a supportive microenvironment for human dermal papilla cells, enhancing their hair-inductive capacity and ability to mimic hair morphogenesis-like events in vitro.

In this animal study, a topical gel containing ethyl-methyl-hydroxypyridine succinate showed potential in accelerating hair regrowth and improving skin biochemical parameters in rats with chemically induced alopecia, suggesting its possible benefit for alopecia related to oxidative stress.

This article reviews temporal triangular alopecia, emphasizing the utility of dermoscopy for diagnosis, and reports no new clinical treatment findings.

This report discusses a 48-year-old patient with androgenetic alopecia and basal cell carcinoma on the right hairline, where forehead reduction surgery and tumor excision were performed simultaneously, improving aesthetics and resolving the cancer issue.

This article reviews a case of alopecia triangularis temporalis, emphasizing the need for histopathological confirmation to avoid misdiagnosis and highlighting surgical correction as the preferred treatment for confirmed cases.

In this case study, a 35-year-old man with recalcitrant folliculitis decalvans was successfully treated with Erbium-YAG laser, showing rapid improvement without hair loss, though further clinical studies are needed to define its benefits more comprehensively.

In this laboratory study, coffee bean residue extract was observed to promote the proliferation of human hair follicle dermal papilla cells by activating autophagy, showing potential for treating hair growth disorders and hair loss.

This source describes two cases of hair transplantation in transgender patients with Androgenetic Alopecia, showing good results using Follicular Unit Extraction and Follicular Unit Transplantation techniques, highlighting the need for more research specific to this population.

This review discusses recent research on exosomes' role in dermatology, highlighting their involvement in skin diseases and rejuvenation and exploring therapeutic possibilities in these areas.

In this article, the researchers emphasized the importance of proper incision angles and careful preparation of the receiving site during eyebrow hair transplants to achieve natural-looking results, highlighting that meticulous planning in design and positioning is crucial.