Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study developed and validated a 50-item questionnaire, the PCOSQ-50, to effectively assess the quality of life in Iranian women with polycystic ovary syndrome, addressing aspects often missed by previous questionnaires.

This study found that conditional knockout of N-WASP in keratinocytes of mice led to skin barrier defects, increased immune cell infiltration, and hyperproliferation of keratinocytes, indicating its crucial role in skin homeostasis.

This study observed that hair follicles in hair loss patients had increased levels of Propionibacterium acnes, potentially linked to elevated immune response gene expression in miniaturized hair follicles.

This study found that conditioned media from epidermal progenitor cells improved skin aging signs in a clinical trial and protected fibroblasts from oxidative stress in vitro.

This study demonstrated that PEGDA hydrogel microwells successfully supported cell survival and proliferation while mimicking hair follicle architecture in vitro, suggesting a potential tool for hair follicle engineering.

In this study, researchers found that deleting Caspase-9 in hair follicle stem cells delayed apoptosis, leading to accelerated wound repair and new hair follicle regeneration by maintaining apoptotic cells as signaling centers.

This study developed lipid-core nanocapsules for encapsulating menthol, improving its solubility and thermal stability, and demonstrated their safety and rapid skin absorption in ex vivo tests, highlighting potential applications for cosmeceuticals.

This study found that the ablation of Esrp1 and Esrp2 disrupts epithelial tight junctions by affecting Arhgef11 isoform expressions, highlighting a potential mechanistic link between splicing alterations and epithelial barrier defects.

This study found that platelet-rich plasma injections improved hair density and diameter in women with androgenetic alopecia not responding to other treatments over 24 weeks, with no adverse events reported.

This study found that Cacumen platycladi extract significantly promoted hair growth and reduced dihydrotestosterone levels by inhibiting 5α-reductase activity in an androgen-sensitive mouse model.

In this study, oral finasteride treatment for four weeks reduced the weight of the corpus cavernosum in rats but did not significantly affect erectile function.

This study achieved a first by successfully forming large quantities of dermal papilla spheroidal microtissues, which retained their hair induction potential, using a micropatterned culture system.

In this study, fractional laser treatment was observed to reverse age-related gene expression changes in skin and enhance dermal remodeling, further improved by multiple treatments.

In this study, a dual recombinase-mediated genetic system showed that cavity macrophages accumulate on the surface of visceral organs during lung and liver injury but do not penetrate or contribute to tissue repair.

This study found that microneedling improved hair density and thickness with minimal side effects in patients with androgenetic alopecia and telogen effluvium.

This study reports that compound heterozygous loss-of-function mutations in the HEPHL1 gene in a child were associated with abnormal hair and cognitive issues, linking altered ferroxidase activity to hair disorders.

This study demonstrated that a bio-3D printed artificial skin scaffold, seeded with adipose-derived mesenchymal stem cells, showed promising wound healing properties by enhancing cell recruitment, migration, and gene expression related to tissue regeneration.

This study found that chemotherapy in female breast cancer patients caused significant early hair loss, which began to recover three months after completion, whereas tamoxifen did not affect hair growth.

This study found that extracellular ATP released from UVB-irradiated keratinocytes promotes melanin production through the P2X7 receptor, indicating a role for ATP-P2X7 signaling in UV-induced melanogenesis.

This study reported that adipose-derived stem cell-conditioned medium demonstrated anti-tumorigenic effects on B16 melanoma cells both in vitro and in vivo, indicating potential for future melanoma treatment.

This study found that keratin coatings from human hair may improve the colony-forming efficiency of human mesenchymal stem cells by moderating donor variability, suggesting a potential use in clinical applications.

This study found that feline superficial pyoderma was more prevalent in the dermatology-referral cats studied than previously reported, affecting mainly young cats with hypersensitivities and manifesting various lesion types.

This article reviews the interaction between sex hormone pathways and morphogenesis-related signaling in epithelial organ development, using a chicken model to propose testable hypotheses, but reports no new clinical results.

This study found that in wound-induced hair neogenesis, African spiny mice and laboratory mice exhibit different morphogenetic field formation patterns related to tissue stiffness, suggesting evolutionary developmental biology advantages.

This study found that lymphatic vessels promote hair follicle growth in mice and may represent new therapeutic targets for hair loss conditions.

This study found that thermoresponsive hydrogels can maintain mechanical memory in fibroblasts, enhancing wound healing compared to traditional trypsinized methods.

In this study, CD109 overexpression in transgenic mice led to reduced inflammation and improved collagen organization during wound healing without affecting wound closure.

This study found that androgen signaling has complex effects on bone formation in male AR3.6-transgenic mice, with varying impacts based on the embryonic lineage of cells.

This study investigated the use of dissolving microneedle patches to improve the skin-lightening effects of alpha-arbutin and resveratrol, finding that the patches enhanced intradermal delivery and slightly decreased the melanin index without affecting skin hydration or causing irritation over 24 hours.

This study found that certain keratin gene mutations associated with pachyonychia congenita are linked to altered enamel structure and increased risk of dental caries.