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This review discusses how inflammation influences hair follicle stem cell activities like wound healing and follicle cycling and suggests a potential link between inflammation, stem cell activation, and programmed cell death.

This article reviews major uses of platelet-rich plasma in treating various hair disorders, including both non-cicatricial and cicatricial alopecia, but reports no new results.

This review discusses the mechanisms underlying immune tolerance failure in alopecia areata and highlights potential therapeutic avenues for restoring hair growth and achieving sustained remission, but reports no new clinical results.

This review discusses the challenges in identifying specific hair follicle antigens involved in initiating alopecia areata and highlights the need for further research to understand its etiopathogenesis, reporting no new results.

This study reports that immunologically inert and skewed immune cell populations in developing human skin may contribute to wound healing and structural changes during skin development.

This source reports that a network meta-analysis found oral baricitinib and ruxolitinib to be effective and safe for treating alopecia areata, significantly improving response rates over placebos and showing fewer adverse effects than steroid treatments, though precise dosing needs further study.

This study identified peripheral myeloid cells as the earliest dysregulated immune cells in PINK1 KO mice with Parkinson’s-like symptoms following intestinal infections, suggesting that PINK1 regulates gut immune functions linked to early Parkinson’s disease mechanisms.

This review provides an in-depth analysis of the structure and function of c-kit activation, and its role in both normal physiological and pathological conditions, with no new research findings reported.

This review summarizes the current treatment modalities for frontal fibrosing alopecia and provides a practical guide for clinicians, but reports no new clinical results.

In this study, 70 patients with alopecia areata who received intralesional triamcinolone showed a significant reduction in black dots, yellow dots, broken hair, and tapering hair, while achieving a 60% success rate in hair regrowth.

This study found that lichen planopilaris in men typically presents similarly to women, with a lower likelihood of nonscalp hair loss and a higher association with mucosal lichen planus and thyroid disease.

This review article examines the current understanding of frontal fibrosing alopecia, noting its prevalence in different demographics and the roles of genetic and environmental factors in its pathogenesis, while highlighting that treatment approaches remain varied and lack standardization.

This study found that both superficial cryotherapy and intralesional corticosteroid injections significantly improved hair growth in patients with alopecia areata, with similar efficacy between the two treatments, establishing cryotherapy as a simple and noninvasive treatment option.

Stem cell research and regenerative medicine have made significant advancements in treating various diseases and conditions.

This study describes a new treatment algorithm for alopecia areata that includes both disease severity and quality-of-life considerations, highlighting recent therapeutic advances and the need for future validation and access equity.

In this report, researchers described a 36-year-old woman with frontal fibrosing alopecia resistant to standard treatments, who showed significant improvement after six months on a combination of intralesional betamethasone and oral hydroxychloroquine, suggesting potential benefits of this therapy approach in managing the condition.

This study provides a framework for understanding different types of alopecias based on immune privilege collapse at specific follicular sites, revealing distinct patterns in immune effector programs and stromal influences depending on the alopecia type.

In this study, cicatricial alopecias were classified by inflammatory cell type and the researchers highlighted that primary cicatricial alopecia's exact causes remain unknown, accounting for 6% of all hair diseases despite its unclear prevalence.

This review integrates studies on mouse models and human clinical observations to highlight the role of immune cells in skin development and how their dysregulation leads to skin disorders, suggesting potential therapeutic pathways for skin regeneration.

This research highlights selenium's critical roles in various biological processes and underscores the potential health impacts of both its deficiency and excess, including increased mortality risk, poor immune function, and neurological issues.

This review highlights new treatment options for alopecia, including JAK inhibitors and Wnt pathway-targeting therapies, which may offer better efficacy and safety than traditional treatments like minoxidil and finasteride, but notes the need for more research on long-term effects and patient-specific responses.

This review discusses the various off-label treatments for alopecia areata, highlighting that these therapies may promote hair growth but are not curative.

In this study on mice, researchers observed that dermal white adipose tissue (dWAT) plays a key role in regulating skin inflammation and tissue repair; however, reduced expression of certain cytokines in obese mice may hinder these processes, indicating potential metabolic disruptions in dWAT during inflammation.

This study reviews the range of both conventional and unconventional treatments for Alopecia Areata, highlighting the promise of biological therapies like JAK inhibitors, but notes more research is needed to optimize treatment effectiveness and personalization.

This study demonstrated that disrupting EGFR signaling in mice leads to immune sensitivity compromising the hair follicle's protective environment, but JAK1/2 inhibition can restore this immune privilege and stimulate hair growth, suggesting a potential therapy for scarring hair loss diseases like cicatricial alopecia.

This study constructed a comprehensive atlas of prenatal human skin, revealing that innate immune cells, such as macrophages, play a crucial role in skin morphogenesis by interacting with non-immune cells, influencing hair follicle formation and angiogenesis beyond their traditional immune functions.

This literature review highlights challenges in managing alopecia areata in the Middle East and Africa, noting significant regional gaps in data, treatment guidelines, and public awareness that impede patient care and emphasize the need for improved support and resources.

This review examines current treatments for alopecia areata, noting that topical corticosteroids are commonly used first in children, while more advanced cases may require systemic therapies to modulate the immune system; it reports no new clinical results.

This study provides evidence that innate lymphoid cells-type 1 can induce alopecia areata in human hair follicles, challenging the view that it is solely a CD8+ T cell-driven autoimmune disease.

This study found that type 2 immunity, especially involving ILC2 cells, helps maintain skin homeostasis by regulating the proliferation and community stability of hair follicle epithelial cells in the presence of Demodex mites.