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This study found that topical application of Astragalus membranaceus extract induced hair regrowth and reduced immune response markers in mice with natural hair loss.

In this review, researchers found that TNF-α, IL-17, and JAK inhibitors show the most promise for stabilizing and resolving scarring alopecias, with IL-23 and Interferon Alpha Receptor 1 inhibitors also providing some benefits in managing these hair loss conditions.

This abstract discusses the role of advanced glycation end-products in aging-related skin damage, but does not provide new findings on their impact on alopecia.

This study found that stimulating toll-like receptor 5 via mucosal delivery of a flagellin-containing fusion protein effectively extended lifespan and enhanced healthspan in mice, including improved bone density and cognitive capacity.

In this study, researchers found that cytokine dysregulation linked to genetic background is present in both patients and healthy but genetically related individuals in two autoimmune skin diseases, Pemphigus vulgaris and Alopecia areata, suggesting that protective immune mechanisms may prevent disease manifestation in predisposed individuals.

This study found that combining excimer light at 308 nm with tacrolimus 0.1% was more effective in treating alopecia areata of the scalp compared to excimer light alone, as indicated by a greater reduction in the SALT score and better improvement in Treg function.

This review outlines the proposed theories behind the development of alopecia areata, emphasizing the autoimmune process involving lost immune privilege in hair follicles, and stresses the need to pinpoint specific pathogenic mechanisms for potential treatments.

In this review, the authors report that tacrolimus ointment shows promise for expanding its use to a variety of skin conditions, beyond its current approval for atopic dermatitis, by analyzing clinical experiences of its application for rosacea, seborrheic dermatitis, psoriasis, and other dermatoses.

This study observed that transgenic mice with overexpression of HE4 developed keratitis and severe corneal opacity, suggesting that HE4 may significantly influence keratopathy and inflammatory responses in the eye.

This article reviews the current FDA-approved treatments for severe pediatric alopecia areata, including the use of Janus kinase inhibitors, but reports no new clinical findings.

This study found that type 2 immunity, especially involving ILC2 cells, helps maintain skin homeostasis by regulating the proliferation and community stability of hair follicle epithelial cells in the presence of Demodex mites.

This source describes a previous case report that combined anthralin and calcipotriene to treat alopecia areata, showing promising results, but highlights that further research is needed to understand the mechanisms and potential benefits of this combination therapy.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

The document concludes that low-dose acne treatment is most suitable for moderate acne, with high patient satisfaction and low relapse rates.

This study found that a significant portion of alopecia areata patients achieved at least partial hair regrowth with diphenylcyclopropenon therapy, which was more effective in certain subtypes and disease durations.

This review explores the causes and mechanisms of alopecia areata and discusses current treatments, reporting no new clinical findings.

This review discusses the role of immune privilege collapse in the pathogenesis of alopecia areata, emphasizing the potential for therapeutic manipulation of hair bulb immune privilege to offer new treatment options, and reports no new results.

This study found that Sonic Hedgehog secreted by hair follicle transit-amplifying cells is essential for dermal adipogenesis and hair follicle growth by acting on adipocyte precursors.

This review discusses the causes, clinical presentation, and management of anagen effluvium, emphasizing its psychological impact and the need for empathy and practical support, but reports no new results.

In this study, proliferative and necrotizing feline otitis externa in four domestic shorthair cats improved with topical 0.1% tacrolimus treatment, despite previous ineffective therapies.

This review discusses the emerging roles of transit-amplifying cells in tissue regeneration and cancer formation, highlighting their significance beyond a mere transitional state in hair follicles and the hematopoietic system.

This article provides a guide for surgeons on repairing poorly executed hair transplants, emphasizing meticulous techniques and optimal use of limited hair supply to achieve cosmetic improvements.

This review discusses various treatment options for alopecia areata tailored by age and severity, providing a practical algorithm, but reports no new clinical results.

This review examines nonmalignant skin toxicities from immunosuppressive and transplant-related medications, emphasizing the need for effective identification and management by care providers; it presents no new research findings.

This review critically assesses current topical therapies for scalp psoriasis and reports no new clinical results; the authors highlight the need for controlled trials to evaluate treatment efficacy.

This study observed that zinc deficiency in humans and mice was associated with diminished allergic contact dermatitis but increased severity and duration of irritant contact dermatitis.

This review discusses topical calcineurin inhibitors for cutaneous lupus erythematosus and reports no new clinical findings; the authors emphasize the need for more comparative studies with corticosteroids.

This review highlights recent advances in pediatric dermatologic treatments, including the use of propranolol for infantile hemangiomas and etanercept for plaque psoriasis, but it reports no new clinical results.

This literature review highlights the effectiveness of topical vitamin D (e.g., calcipotriol, calcitriol) in treating vitiligo, emphasizing its role in melanogenesis and as an immunomodulator, either alone or combined with topical corticosteroids, offering minimal side effects.

In this randomized trial, lupus patients taking daily 200 μg selenium supplements for eight weeks showed significant improvements in metabolic markers like CRP, ESR, MDA, and GPX, as well as reduced clinical symptoms such as arthritis and alopecia, compared to those receiving a placebo.