7 citations
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January 2025 in “Frontiers in Microbiology” In this study, researchers investigated the immunohistopathological characteristics of the skin in individuals during the acute phase of chikungunya infection, revealing CHIKV antigens and inflammatory infiltrates in various skin components and highlighting the role of cytokines/chemokines in the disease's skin manifestations.
4 citations
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June 2024 in “British Journal of Dermatology” This study found that treatment with EGFR inhibitors or mitogen-activated kinase inhibitors may compromise the immune privilege of human scalp hair follicles, suggesting new directions for managing drug-induced folliculitis.
4 citations
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July 2018 in “Molecules” This study found that blood and milk somatic cells show promise as matrices for monitoring illicit recombinant bovine somatotropin use in dairy cattle through gene-expression assays.
1 citations
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September 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” This article reviews a variety of research presentations from the Society for Investigative Dermatology's annual meeting, highlighting advances in dermatological research without reporting new clinical results.
July 2025 in “Journal of Investigative Dermatology” July 2022 in “British Journal of Dermatology” This study found that epidermal growth factor receptor inhibitors used in cancer treatment induce a distinct inflammatory response in hair follicles, marked by immune privilege collapse and upregulation of inflammatory pathways.
March 2005 in “Journal of the American Academy of Dermatology” Higher levels of IL-1a and IL-1RA were found in severe alopecia areata cases.
July 2024 in “Journal of Investigative Dermatology” ATR04-484 ointment shows promise for treating skin issues from cancer therapies.
June 2026 in “Journal of Obstetrics Gynecology and Cancer Research” In this study, women with PCOS exhibited a significantly elevated low-grade inflammatory profile through salivary cytokines, with IL-1β and TNF-α demonstrating strong potential as non-invasive diagnostic markers, alongside traditional androgen measures like FAI.
20 citations
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November 2017 in “JAAD case reports” This case report describes a patient with psoriasis, vitiligo, and alopecia areata who showed significant improvement in all conditions after treatment with ustekinumab, suggesting potential benefits of IL-12/23 blockade for these autoimmune diseases.
20 citations
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February 2017 in “International Journal of Dermatology” This study found that the small molecule honokiol may protect against inflammation, collagen breakdown, and cell damage caused by cigarette smoke in skin cells cultured in vitro.
18 citations
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April 2021 in “Experimental Dermatology” This study in Italy observed telogen effluvium and trichodynia as common hair-related complications following COVID-19 infection, raising questions about underlying hair follicle biology and potential receptor involvement.
16 citations
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November 2005 in “Journal of Investigative Dermatology Symposium Proceedings” This study found that intramuscular anti-IFN-γ significantly stabilized and promoted hair regrowth in alopecia areata patients with patchy, progressive hair loss, whereas those with total baldness showed more limited improvement.
14 citations
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March 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that serum MIF levels were significantly higher in patients with extensive alopecia areata compared to those with mild alopecia areata and healthy individuals.
6 citations
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July 2013 in “Experimental and Therapeutic Medicine” This study found that topical ginsenoside Rg1 may protect skin from UVB-induced damage in mice by reducing pathological changes and modulating cytokine mRNA expression associated with inflammation and immune response.
1 citations
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December 2024 in “Indian Dermatology Online Journal” This research notes that biologics and small molecules are effective for treating nail psoriasis and alopecia areata, albeit with precautions for adverse events, but no clinical trials have been published for their use in treating nail lichen planus and atopic dermatitis.
January 2026 in “Journal of the Egyptian Womenʼs Dermatologic Society” This study observed that male patients with alopecia areata had elevated serum levels of HSP70 and IL-15, with levels increasing alongside disease severity, suggesting these markers are strongly associated with the disease's pathogenesis.
This study found that the Nap-F3K-CA hydrogel, when used on burn wounds, demonstrated effective antibacterial and anti-inflammatory properties, promoting accelerated skin repair, decreased wound infections, and improved healing processes, highlighting its potential as a clinical burn wound dressing.
July 2016 in “Cancer Research” This study developed a topical botanical lotion for managing chemotherapy-induced hair loss in cancer patients, reporting that it improved hair recovery times by 5-16 weeks, reduced inflammation, and enhanced scalp collagen levels with no observed side effects.
November 2025 in “The Journal of Dermatology” In this case report, a Japanese woman with both atopic dermatitis and alopecia areata showed improvement in both conditions following treatment with nemolizumab.
7 citations
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April 2023 in “Biomedicines” This study found that sex hormones, specifically non-aromatizable androgens like DHT and A/T, significantly increase inflammatory cytokine expression in human adipocytes when stimulated by LPS.
1 citations
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January 2017 in “Springer eBooks” This review discusses recent advances in understanding alopecia areata's disease mechanisms and highlights JAK molecules as promising therapeutic targets, but reports no new clinical results; controlled trials are needed.
March 2026 in “Biomedicines” This review synthesizes current evidence on therapies for dissecting cellulitis of the scalp, noting that biologics show promise for treatment-resistant cases, though systemic retinoids remain the first-line therapy.
January 2026 in “Cosmetics” In this study, yeast fermentation of Platycladus orientalis leaves was shown to enhance hair growth-promoting properties by affecting cell cycle phases in human dermal papilla cells, increasing growth factor VEGF, reducing inflammatory factor TGF-β1, and altering the expression of Wnt/β-catenin pathway-related genes.
September 2025 in “Diseases” This study found that patients with patchy alopecia areata had significantly higher serum levels of pro-inflammatory cytokines IL-6, TNF-α, IL-17A, and IL-21 compared to healthy controls, with these levels correlating positively with disease severity, age, and disease duration.
January 2024 in “Biomedicines” This review discussed the cutaneous manifestations of APECED, highlighting chronic mucocutaneous candidiasis, alopecia areata, and vitiligo, while emphasizing the importance of early detection and monitoring for accurate diagnosis and patient care in various populations.
January 2019 in “Springer eBooks” Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.
October 2012 in “Humana Press eBooks” This article discusses the historical and current uses of grape seeds in various industries but reports no new research findings.
40 citations
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August 2022 in “Frontiers in immunology” This review discusses the potential of JAK inhibitors as a promising treatment strategy for alopecia areata, highlighting their mechanism and recent FDA approval based on clinical trial efficacy.
2 citations
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September 2022 in “Frontiers in Immunology” This article reviews the emerging non-inflammatory roles of regulatory T cells in the skin and reports no new clinical findings, suggesting broad biological influence beyond traditional immune functions.