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This study demonstrated that a new topical treatment using ketotifen-loaded microneedles, designed for prolonged release, significantly reduced inflammatory markers in an animal model of allergic conjunctivitis, suggesting enhanced therapeutic delivery and sustained ocular benefits.

This study found that Euph E and Euri A showed strong anti-inflammatory activity and modulated cytokine and immune functions in macrophages, related to specific signaling pathways.

This study found that Xinyang Tablet may improve cardiac function in LPS-induced sepsis-induced myocardial dysfunction by modulating macrophage polarization and autophagy through affecting LncSICRNT1 and TRAF6 expression.

In this study, dry powder inhalers containing Cepharanthine were administered to rats with acute lung injury, significantly reducing pulmonary edema, hemorrhage, and inflammatory markers, suggesting its potential as an effective anti-inflammatory treatment when inhaled directly into the lungs.

This study reported that dutasteride, identified through a drug repurposing strategy, showed the potential to reduce neuroinflammation and cognitive impairment in LPS-stimulated models.

This review examines host factors like ACE2 and TMPRSS2 in SARS-CoV-2 infection, exploring how genetic variants and advanced cellular analyses might clarify COVID-19's severity and heterogeneity; it reports no new results.

In this study, researchers found that a specific Sargassum horneri extract processed via low-temperature pulverization improved burn wound healing in mice by enhancing re-epithelialization and reducing inflammation and oxidative stress, highlighting its potential as a therapeutic candidate.

In a study using diabetic rats, researchers found that oral empagliflozin accelerated wound healing by reducing inflammation and oxidative stress, indicating potential benefits beyond blood sugar control for managing diabetic wounds.

This study suggests that human placenta hydrolysate reduces CFA-induced inflammatory pain in mice by inhibiting pro-inflammatory cytokines and protecting peripheral nerves.

This study suggests that Gujian oral liquid may reduce osteoarthritis symptoms by regulating inflammation and catabolism through the TNF-α/NF-kappa B signaling pathway, as confirmed by both in vivo and in vitro experiments.

This study found that a postbiotic derived from hawthorn and probiotics can alleviate loperamide-induced constipation in aged mice by regulating several physiological processes, including intestinal water and sodium metabolism, maintaining gut flora and barrier, reducing inflammation, and enhancing short-chain fatty acid metabolism.

This study evaluated a novel synthetic cell-penetrating peptide, DualPep-ALO, finding it promotes hair growth by enhancing follicle cell proliferation, activating regenerative pathways, and reducing inflammation and oxidative stress in vitro and ex vivo, suggesting a promising new topical treatment for hair loss that rivals minoxidil.

In this study, 2′‐Fucosyllactose (2′‐FL) administration significantly reduced hair loss and increased hair length and thickness in a testosterone-induced androgenic alopecia mouse model, suggesting potential as a therapeutic agent for AGA.

This study found that complete COVID-19 vaccination significantly reduces the risk of developing long COVID symptoms, with factors like age, female gender, and obesity increasing persistence of symptoms.

In this study, combining Ginkgo biloba extract dropping pills with butylphthalide capsules improved cognitive and neurological function, daily living activities, and reduced inflammatory responses in patients with cognitive dysfunction following an acute ischemic stroke, compared to butylphthalide treatment alone.

This review paper discusses the effectiveness of repurposed drugs and potential novel therapies for treating COVID-19, highlighting remdesivir as the only FDA-approved medication and listing others with Emergency Use Authorization.

This study explores potential treatments for post COVID-19 complications using natural substances through molecular docking, but reports no new clinical results and existing treatments remain limited to prophylaxis and therapeutics.

The study found that conditioned medium from placental cells and sub-cultured placental tissue promoted angiogenesis in HUVECs, with early pregnancy cells showing more significant effects than those from full-term pregnancy.

This study found that conditioned medium from human placental cells or tissue promoted angiogenesis in HUVECs in vitro, with early-pregnancy placental cells and whole placental tissue showing more significant effects.

This article lists online educational resources from the American Society of Plastic Surgeons but reports no new research findings.

This study found that SRD5A2 expression is absent in one third of benign adult prostates and is associated with hypermethylation, suggesting potential personalization of treatment for prostatic diseases based on methylation status.

This review discusses the role of complement activation in autoimmune diseases and explores the potential for anti-complement therapies as a new treatment strategy, without reporting new clinical results.

This study investigated the effects of Taohong Siwu Decoction on deep vein thrombosis, identifying 56 potential targets and highlighting beta-sitosterol, quercetin, and kaempferol as key active components that may regulate inflammation through the PI3K/Akt pathway, potentially slowing disease progression.

This study highlights that biological therapy, which stimulates the immune system through various methods like cytokine injections and immune checkpoint inhibition, shows promise for treating melanoma based on laboratory and clinical studies.

This review analyzes the interplay between atopic dermatitis and alopecia areata, suggesting that epidermal barrier dysfunction and genetic predispositions exacerbate both conditions through immune responses.

In this case-control study, individuals with alopecia areata showed significantly elevated levels of inflammatory markers IL-4, IFN-γ, and CRP, as well as reduced serum Folate and Ferritin, suggesting the condition's multifactorial pathophysiology involves immune activation, systemic inflammation, and micronutrient deficiencies.

This review outlines the proposed theories behind the development of alopecia areata, emphasizing the autoimmune process involving lost immune privilege in hair follicles, and stresses the need to pinpoint specific pathogenic mechanisms for potential treatments.

This study examined immune responses to Diphencyprone and found that its induced skin reactions have higher levels of negative immune regulators compared to psoriasis, suggesting differences in immune regulation may contribute to psoriasis chronicity.

This study identified 1277 genomic regions selected for traits in indigenous Chinese goats, including cashmere fiber, reproduction, size, and high-altitude adaptation, revealing key candidate genes for these phenotypes through whole-genome resequencing.

This study found that γδ T cells play a role in regulating stromal behavior, influencing the composition and vascularity of fibrotic tissues during the foreign body response.