49 citations,
October 2017 in “Nutrients” Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.
6 citations,
October 2021 in “Biomedical Research and Therapy” Alopecia areata patients have higher levels of IL-6 and TNF-α.
1 citations,
February 2022 in “Experimental Dermatology” Certain proteins are found at higher levels in balding areas compared to non-balding areas, suggesting a link to hair loss. This could be useful for diagnosing and treating hair loss.
December 2023 in “International journal of multidisciplinary research and analysis” SH-MSCs gel reduced IL-6 and increased TGF-β, suggesting it could treat alopecia.
Higher levels of certain proteins in hair loss areas may help understand and treat hair loss.
16 citations,
January 2016 in “Journal of Investigative Dermatology” Mice without the IL-6 gene had more hair growth after injury due to higher activity of a related protein, Stat3.
14 citations,
November 2019 in “Mediators of inflammation” IL-6 from stem cells helps repair skin and grow hair.
11 citations,
November 2015 in “Experimental Dermatology” The conclusion is that the IL-6/STAT3 activation affects p63 expression in healing wounds, which may help in hair follicle regeneration.
9 citations,
July 2022 in “EMBO molecular medicine” Blocking certain immune signals can reduce skin damage from radiation therapy.
January 2009 in “한방재활의학과학회지” Saengbal-eum-2 promotes hair growth and reduces inflammation in mice.
9 citations,
August 2017 in “Photochemistry and Photobiology” Red light at 627 nm can safely trigger IL-4 release in skin cells, potentially helping treat inflammatory skin conditions.
4 citations,
November 2017 in “PubMed” Your genes, especially IL-1a, can predict how well a hair growth treatment with platelet rich plasma will work for you.
September 1997 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Anti-IL-1 treatments might help with certain types of hair loss in people with high inflammation.
20 citations,
March 2019 in “Case Reports in Dermatology” IL-17 inhibitors for psoriasis may cause unexpected hair loss.
September 1997 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Blocking IL-1 could help treat some hair loss conditions; alopecia affects liver detox systems; spironolactone is better than finasteride for female hair growth; focusing on the catagen hair phase could lead to new alopecia treatments.
717 citations,
June 2010 in “Nature” Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.
128 citations,
August 2015 in “Cell Stem Cell” Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.
127 citations,
January 2000 in “Journal of Investigative Dermatology” Cytotoxic T cells cause hair loss in chronic alopecia areata.
114 citations,
January 2021 in “medRxiv (Cold Spring Harbor Laboratory)” COVID-19 can cause over 50 long-term symptoms, with fatigue and headache being the most common.
69 citations,
September 2006 in “Human Reproduction” Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.
65 citations,
June 2020 in “Stem Cell Research & Therapy” Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
56 citations,
September 2016 in “Pharmaceutical Research” The fish oil-based gel with imiquimod improves skin cancer treatment and reduces inflammation.
48 citations,
January 2000 in “Hormone Research in Paediatrics” Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.
37 citations,
December 2021 in “Cells” Alopecia areata severity and treatment response are linked to specific cytokine levels.
35 citations,
January 2017 in “Journal of Dermatological Science” Stress can cause early aging in certain skin cells, leading to problems with hair growth.
32 citations,
March 2021 in “Journal of cosmetic dermatology (Print)” COVID-19 infection may trigger alopecia areata in some patients.
32 citations,
December 2009 in “Archives of Dermatological Research” Dihydrotestosterone increases certain inflammatory signals in skin cells, potentially contributing to acne.
29 citations,
March 2020 in “Stem Cell Research & Therapy” Fat stem cells from diabetic mice can help heal skin wounds in other diabetic mice.
28 citations,
November 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” GMG-43AC may help reduce unwanted hair growth and treat certain hair loss conditions.
26 citations,
April 2019 in “Advances in wound care” Tannic acid helps wounds heal faster in rats by activating certain cell signals and reducing inflammation.