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Blocking IL-12 can help treat alopecia areata by preventing hair follicle immune issues.

IL-18 signaling helps mature Tregs move into the thymus.

IL-18 signaling helps mature Tregs move into the thymus.

Collagen VII helps skin heal and stay strong, sirolimus may lower skin cancer risk in kidney transplant patients, high-molecular-mass hyaluronan helps naked mole rats resist cancer, dermal γδ T cells aid in hair growth in rodents, and overexpression of IL-33 in mouse skin causes itchiness, offering a model for studying allergic inflammation treatments.

Small molecule DMF improves psoriasis and multiple sclerosis, adult skin cells can be made to grow new hair, certain skin cells initiate hair growth, IL-17C controls gut health and can cause skin inflammation, and skin cells produce IL-17 that can lead to psoriasis.

Anti-IL-1 treatments might help with certain types of hair loss in people with high inflammation.

Blocking IL-1 could help treat some hair loss conditions; alopecia affects liver detox systems; spironolactone is better than finasteride for female hair growth; focusing on the catagen hair phase could lead to new alopecia treatments.

Aging disrupts skin repair and stress responses, but exercise-related IL-15 improves wound healing and skin health in older skin.

New findings suggest targeting IL-23 could treat psoriasis, skin cells can adapt to new roles, direct conversion of skin cells to blood cells may aid cell therapy, removing certain tumor cells could boost cancer immunotherapy, and melanoma may have many tumorigenic cells, not just cancer stem cells.

Controlled delivery of specific RNA and IL-4 restored hair growth in mice with autoimmune alopecia.

Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Probiotic bacteria improved skin and hair health in aged mice.

Cytotoxic T cells cause hair loss in chronic alopecia areata.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

COVID-19 can cause over 50 long-term symptoms, with fatigue and headache being the most common.

Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

Animal models have helped understand hair loss from alopecia areata and find new treatments.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.

Tph cells are linked to the severity of systemic lupus erythematosus.

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

Corticosteroid treatment reduces inflammation and alters hair keratins in alopecia areata.

Keratin 17 is linked to various diseases, including cancer and skin conditions, and may be a target for diagnosis and treatment.