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The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Special fiber materials boost the healing properties of certain stem cells.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Oxidative stress contributes to hair graying and loss as we age.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.

Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.

Sunlight worsens hair loss; protect scalp.

Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.

The silk fibroin-based hydrogel shows promise for treating melanoma and healing infected wounds by killing tumor cells and bacteria, and supporting skin recovery.

SHBG may be a useful early indicator and treatment target for PCOS.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.

Platelet-rich plasma, taken from a person's own blood, can help rejuvenate skin, stimulate hair growth, and treat hair loss, but more research is needed to confirm its safety and effectiveness.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.