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This study found that the ARL15 gene affects adipocyte differentiation and adiponectin secretion, and suggests that ARL15 haploinsufficiency may predispose individuals to lipodystrophy.

This bibliometric analysis identified the top 100 most cited articles on alopecia areata from the past 50 years, highlighting key research trends, with treatment studies being the most common focus and the Journal of the American Academy of Dermatology as the most published journal.

T cells and bacteria in the gut and skin help maintain health and protect against disease.

IL-13 protein is much higher in the skin of atopic dermatitis patients than in healthy skin.

This study found that IL-25-mediated-IL-17RB signaling improved diabetic wound healing by enhancing angiogenesis, collagen deposition, and endothelial cell function, suggesting a potential therapeutic strategy for poorly healing diabetic wounds.

In this study, researchers identified IL18R+ thymus-resident regulatory T cells in mice, demonstrating their unique molecular features and resistance to age- and stress-induced thymus involution, highlighting IL18 signaling's role in Treg migration and retention.

This study reviewed recent theories on alopecia areata's pathogenesis, highlighting its autoimmune nature due to immune privilege disruption in hair follicles, and noted current treatments have limited efficacy with high relapse rates, underscoring the need for further research into its mechanisms for better therapies.

This review noted that alopecia areata is an autoimmune disease impacting hair follicles and offered insights into its complex pathogenesis involving immune responses, while highlighting ongoing research into new treatments such as Janus kinase inhibitors and other immunomodulatory drugs.

In this study, three patients with extensive alopecia areata showed varying degrees of hair regrowth after 20 weeks of treatment with ustekinumab, a cytokine-targeting therapy.

This study found a direct correlation between IL6 and insulin, glucose, and cholesterol serum levels in patients with oral lichen planus, suggesting a potential increased cardiovascular risk.

In this study, subcutaneous recombinant human IL-12 showed a 43% partial response rate in early-stage mycosis fungoides patients refractory to previous treatments, with generally mild to moderate adverse events reported.

This study found that knock-down of keratin 15 in various cell lines affected cell spreading, morphology, migration, differentiation, and proliferation, suggesting its role in maintaining the stem cell nature of keratinocytes.

This study found that IL-1α promotes hair follicle regeneration and stem cell activation in an age-dependent manner by modulating inflammatory cells and oxidative stress in mice.

This review discusses the pathogenesis, clinical presentation, diagnosis, and treatment of cutaneous lupus erythematosus, reporting no new clinical findings.

This review outlines the advancements in organ and tissue transplantation since the discovery of the human MHC and reports no new clinical results.

This review discusses the role of the JAK-STAT pathway in autoimmune skin diseases and suggests potential therapeutic benefits of JAK inhibitors, but reports no new experimental results.

This review discusses the role of regulatory T cells in skin, including their impact on hair follicle regeneration, wound healing, and immune tolerance, without presenting new clinical findings.

In this phase I study, partial hair regrowth was observed in patients with alopecia universalis using topical JAK inhibitors, though more research is needed to confirm potential as a treatment alternative to clobetasol.

This review examines the role of regulatory T cells in skin immune disorders, highlighting their unique functions in conditions like scleroderma, alopecia areata, and psoriasis, without reporting new clinical results.

This article discusses the potential of oral tofacitinib as a treatment for atopic dermatitis, alopecia areata, and vitiligo, without presenting new clinical results.

This study found that oral tofacitinib led to clinically significant improvement in alopecia areata severity scores among pre-adolescents, though results varied and further evaluation in clinical trials is needed.

This study explored hair follicle gene expression in Inner Mongolia Cashmere goats and identified potential regulators of the transition between growth phases, including IL17RB and ZNF genes.

This review discusses the development of Janus kinase inhibitors for dermatologic diseases and reports no new results; the authors note the need for further research on their efficacy and safety.

This article is a Letter to the Editor discussing rebound effects associated with JAK inhibitor use in treating alopecia areata and reports no new clinical results.

In this case report, the authors describe a child with treatment-resistant alopecia areata who successfully responded to leflunomide and anthralin, proposing this combination as a potentially cost-effective alternative for managing recalcitrant cases by possibly inhibiting the JAK/STAT pathway.

This study reviewed the prospects and challenges of using stem cells from adipose tissue in regenerative medicine for facial rejuvenation, emphasizing the need for further research to ensure patient safety before these methods can become routine in cosmetic and reconstructive surgery.

This study found that modeling and simulation effectively informed decision-making and dose selection for ritlecitinib in treating alopecia areata, supporting an accelerated drug development strategy.

This review examines the mechanisms of Janus kinase inhibitors in treating alopecia areata and evaluates their efficacy and safety, but reports no new clinical results.

This study presents a rare case of alopecia totalis occurring after the use of permanent hair dye.

This study suggests that hydroxypinacolone retinoate (HPR) may be an effective alternative to tretinoin for anti-aging skin treatments, offering similar collagen production benefits without increased skin irritation.