Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that γδ T cells in the skin contribute to wound healing after vaccinia virus infection by promoting cytokine and growth factor induction, without affecting virus replication control.

This study found that oral administration of Flammulina velutipes polysaccharide reduced tumor volume and improved survival in mice by modulating macrophage polarization and enhancing antitumor immune responses.

This study found that repeated oral intake of 0.5 or 5 mg/kg of cobalt ferrite nanoparticles induced pulmonary toxicity in rats, with dose-dependent oxidative stress and inflammation observed, but no notable toxicity was seen at a 0.05 mg/kg dose.

This study demonstrated that a new topical treatment using ketotifen-loaded microneedles, designed for prolonged release, significantly reduced inflammatory markers in an animal model of allergic conjunctivitis, suggesting enhanced therapeutic delivery and sustained ocular benefits.

This study found that Xinyang Tablet may improve cardiac function in LPS-induced sepsis-induced myocardial dysfunction by modulating macrophage polarization and autophagy through affecting LncSICRNT1 and TRAF6 expression.

This study reported that dutasteride, identified through a drug repurposing strategy, showed the potential to reduce neuroinflammation and cognitive impairment in LPS-stimulated models.

This study suggests that T-cell recruitment, thrombosis, and increased vascular permeability may contribute to various symptom clusters in post-acute sequelae of COVID-19 through shared cytokine elevation.

This study found that complete COVID-19 vaccination significantly reduces the risk of developing long COVID symptoms, with factors like age, female gender, and obesity increasing persistence of symptoms.

In this animal study, researchers found that the simultaneous deletion of ERBB2 and ERBB3 in mice results in impaired skin differentiation, inflammation, and sebaceous gland alteration, leading to skin lesions, while highlighting potential side effects in cancer therapies targeting these receptors.

This study found that injecting mouse hair follicle-derived mesenchymal stem cells (moMSCORS) into C57BL/6 mice reduced the incidence and severity of type 1 diabetes by modulating immune responses, suggesting potential for therapeutic use due to their immunosuppressive effects.

In this study, combining Ginkgo biloba extract dropping pills with butylphthalide capsules improved cognitive and neurological function, daily living activities, and reduced inflammatory responses in patients with cognitive dysfunction following an acute ischemic stroke, compared to butylphthalide treatment alone.

The study found that conditioned medium from placental cells and sub-cultured placental tissue promoted angiogenesis in HUVECs, with early pregnancy cells showing more significant effects than those from full-term pregnancy.

This study found that proretinal nanoparticles, applied topically, are safe and effective for penetration into hair follicles, enhancing retinoid biological activity in the skin while reducing irritation compared to conventional retinal formulations.

This study found that kaempferol increased the proliferation potential of basal epidermal cells in three-dimensional skin models by enhancing integrin expression and altering cell morphology.

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

This study found that DC-HIL+ myeloid derived suppressor cells are increased in the blood and skin of patients with cutaneous lupus erythematosus and show immunosuppressive properties.

In this study, researchers found that the cell surface protein Lrig1 plays a crucial role in regulating the suppressive function of regulatory T cells, suggesting it as a potential target for treating autoimmune diseases, as evidenced by experiments in mouse models.

This study found that mackerel-derived fermented fish oil extract and its component DHA promote hair growth by activating anagen pathways in dermal papilla cells.

This study found that IL18 signaling plays a crucial role in the homing and retention of mature regulatory T cells in the mouse thymus, primarily by upregulating the chemokine receptor CCR6.

This study found that deleting specific super-enhancer regions in mice affects CD25 expression in a cell type-specific manner, leading to autoimmune alopecia in some cases and revealing distinct regulatory mechanisms for constitutive and inducible expression of CD25.

This review highlights recent insights into how IL-15 influences T cell responses and contributes to immunopathogenesis in various diseases, suggesting its crucial role in TCR-independent activation and potential in optimizing therapeutic strategies.

In this study, researchers reported that IL-17C plays a key pro-inflammatory role in human skin diseases and may be a promising therapeutic target for inflammatory skin conditions.

This study found that ILC1-like cells can induce alopecia areata in healthy human hair follicles, challenging the traditional belief that the disease is primarily driven by CD8+ T cells.

T cells and bacteria in the gut and skin help maintain health and protect against disease.

This article discusses CD10 immunohistochemistry in prurigo nodularis and reports no new research findings.

This study found that reduced expression of CD200R1 on monocyte-derived macrophages in rheumatoid arthritis patients was significantly associated with higher disease severity and an imbalance in Th17/Treg cells.

Chicken feather gene mutation helps understand human hair disorders.

This study found that applying topical thymidine dinucleotide (pTT) to newborn mice before UV exposure delayed and reduced melanoma development compared to untreated controls.

This review examines the use of apremilast for non-FDA-approved dermatological conditions, noting varied efficacy but a favorable safety profile compared to conventional treatments.