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Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

The enzyme 25 Hydroxyvitamin D 1 α-Hydroxylase is essential for healthy skin and recovery after skin damage.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Early detection and intensive treatment of diseases caused by Staphylococcus aureus toxins are crucial for reducing severe health effects.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Probiotic bacteria improved skin and hair health in aged mice.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

Children, especially teenagers, can get severe SARS-CoV infection with symptoms similar to adults, but they typically recover well with supportive care.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Activating TRPV3 stops human hair growth.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.