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This study found that certain T cell-associated genes were upregulated in dogs with Vogt-Koyanagi-Harada syndrome and vitiligo, suggesting a shared immunopathogenesis with humans.

This study suggests that androgens enhance growth factor production in dermal fibroblasts, which in turn may alter keratinocyte differentiation and contribute to acne lesion formation.

This study found that the miRNA chi-miR-877-3p affects hair follicle cycles in Jiangnan cashmere goats by regulating IGFBP5 gene expression and cell proliferation.

This study reported that IGF2BP2 rs1470579 and IGFBP3 rs2854744 may increase the risk of polycystic ovary syndrome in a Southeastern Iranian population.

In this study, treatment with human follicular keratinocyte-conditioned media improved the trichogenicity of cultured dermal cells by activating key signalling pathways, suggesting its potential use in cell therapy for hair loss.

This study developed a composite hydrogel that delivered multiple proteins, enhancing skin wound healing by accelerating closure and promoting hair follicle regeneration.

This study found that older men with vertex balding have lower circulating levels of the protein IGFBP-3 and higher levels of IGF-1.

This study identified 1277 genomic regions selected for traits in indigenous Chinese goats, including cashmere fiber, reproduction, size, and high-altitude adaptation, revealing key candidate genes for these phenotypes through whole-genome resequencing.

This study found that women with female pattern hair loss had significantly lower serum IGF-1 levels than controls, suggesting a possible role for IGF-1 in this condition.

This study found that women with female pattern hair loss had significantly lower serum IGF-1 levels compared to controls, but no significant association between IGFBP-3 levels and hair loss severity was observed.

In this case-control study, researchers observed that women with female pattern hair loss exhibited significantly lower serum IGF-1 levels than controls, while IGFBP-3 levels showed no significant difference, suggesting a potential role for IGF-1 in the condition.

Secreted inhibitors of Wnt and IGF signaling control hair and tooth development, creating species-specific patterns.

This study found that photobiomodulation-irradiated conditioned medium from human adipose-derived stromal cells enhanced hair growth in mice, suggesting its potential as a treatment for hair loss by increasing growth factor secretion.

This study found that conditioned medium from photobiomodulation-irradiated adipose-derived stromal cells enhanced hair growth in a mouse model of hair loss more effectively than non-irradiated medium, suggesting potential for treating alopecia by boosting growth factor secretion.

This study suggests that APC collagen peptides may accelerate hair growth and promote overall hair health by enhancing cellular proliferation and activating specific signaling pathways in human and mouse models.

This study found that zebrafish and stickleback fish use similar genetic programs for tooth regeneration, despite differences in their dental structures.

This study found that adipose-derived mesenchymal stromal cell secretome, particularly when preconditioned with IFNγ, significantly influences cell motility and anti-inflammatory responses, enhancing its potential as a regenerative therapy.

This study found that zebrafish and sticklebacks, despite differences in their tooth regeneration structures, share a similar genetic program during tooth regeneration, suggesting a conserved "successional dental epithelium" in vertebrates.

This study identified 22 genetic loci potentially linked to body weight and wool traits in Ordos fine-wool sheep, highlighting six candidate genes that could be pivotal in understanding and improving these economically important characteristics.

This review discusses the role of physical activity in healthy aging and reports no clinical results; the authors emphasize the need for integrating exercise into daily life and social settings.

This study suggests that metformin may be more effective than Dianette in treating moderate to severe hirsutism in women with PCOS, while also reducing markers of insulin resistance.

This review discusses the therapeutic use of insulin-sensitizing agents in polycystic ovary syndrome, reporting improved ovulation, insulin sensitivity, and reduction of hyperandrogenism, but calls for larger studies to confirm these effects.

This study found that topical cilostazol promotes hair growth, enhances hair follicle activities, and may serve as a potential treatment for alopecia.

This article reviews the medical history and symptoms related to hyperandrogenism in patients, but reports no new clinical findings.

This article discusses polycystic ovary syndrome (PCOS), its symptoms, and links to insulin resistance and type 2 diabetes, but reports no new research findings; the authors emphasize recognition of features in youth.

This review discusses the roles of Wnt signaling in skin organogenesis and related processes but reports no new experimental results, highlighting areas for future research.

This study found that Polygonum multiflorum extract may promote hair growth by increasing anagen duration and activating dermal papilla cells in human hair follicles, as observed in cultured cell models.

This article reviews the challenges in diagnosing mild hyperandrogenism in adolescent girls, discussing potential causes like PCOS and treatment options, but reports no new clinical results.

Both methods improve hair density and thickness; double-spin may be more effective.

This article reviews the differential diagnosis of mild hyperandrogenism in adolescent girls, discussing potential causes such as PCOS and nonclassic adrenal hyperplasia, but presents no new data.