3 citations
,
February 2025 in “Journal of Investigative Dermatology” Lipocartilage is a new type of tissue that affects hair growth and cartilage regeneration.
2 citations
,
July 2025 in “Frontiers in Veterinary Science” This review highlights that microRNAs (miRNAs) play crucial roles in hair follicle development and cycling in cashmere goats, detailing recent advances in understanding their regulatory functions and potential applications in improving cashmere fiber quality and diagnosing hair disorders.
1 citations
,
November 2025 in “Aging Cell” This review discusses the role of the ectodysplasin A2 receptor as a biomarker and driver of ageing related to inflammation, and its potential therapeutic implications, but reports no new clinical findings.
March 2026 in “International Journal of Molecular Sciences” In this laboratory study, researchers observed that mouse vascular endothelial cells exhibit dynamic changes after exposure to ionizing radiation, including a transient endothelial subpopulation that facilitates vascular-epidermal communication and skin repair, with shifting roles in angiogenesis and immune surveillance over time.
January 2026 in “International Journal of Molecular Sciences” This study found that inhibiting the Hedgehog pathway may reduce proliferation and migration in melanoma, suggesting its potential repurposing as a therapeutic target.
January 2026 in “Journal of Clinical Medicine” This review identified significant associations between glucose dysregulation and various dermatological conditions like psoriasis and acne, suggesting that dietary interventions and probiotics may help manage related inflammation, highlighting the need for holistic treatment approaches for insulin resistance and metabolic syndrome.
January 2026 in “Burns & Trauma” This review synthesizes evidence on how RNA modifications affect wound healing, particularly in skin, bone, and corneal injuries, emphasizing potential therapeutic strategies for burns and trauma in relation to these cellular processes.
June 2025 in “Proceedings of the National Academy of Sciences” In this study, a mouse model with a PIK3CA gain-of-function mutation in Schwann cells revealed unique communication with neighboring cells and a glycolytic shift in peripheral nerves, and early alpelisib treatment significantly improved symptoms, though efficacy declined with delayed administration due to limited drug penetration.
164 citations
,
February 2019 in “Anais Brasileiros de Dermatologia” This study produced a guide for managing adult female acne, addressing its complex nature compared to teenage acne, and providing detailed recommendations on diagnosis and treatment. The authors noted that further research is needed to better understand the condition.
1 citations
,
August 2021 in “Arhivʺ vnutrennej mediciny” This review discusses the role of hormones and other factors in the development of alopecia linked to endocrine disorders, but reports no new clinical results, emphasizing the need for a multidisciplinary diagnostic approach.
November 2014 in “John Wiley & Sons, Ltd eBooks” This review discusses hormones that affect acne and highlights a statistically significant link between a low-glycemic-load diet and reduced acne activity, but reports no new experimental findings.
December 2021 in “INDIGO (University of Illinois at Chicago)” This study used single-cell RNA sequencing to characterize 19 distinct cell populations in sheep hair follicles, uncovering differentiation signatures and intercellular communication that may influence wool curvature and sheep breeding.
November 2021 in “OPAL (Open@LaTrobe) (La Trobe University)” This study identified melatonin as a potential treatment for rosacea and Alzheimer's disease, suggesting it may help by modulating inflammatory and vascular signaling pathways.
138 citations
,
June 2012 in “Genes & Development” This study found that dermal Shh signaling regulates specific dermal papilla signatures essential for maintaining hair follicle development, suggesting that the Shh-Noggin signaling loop is crucial for hair morphogenesis.
13 citations
,
May 2022 in “Cell discovery” This study used single-cell RNA sequencing to create a detailed atlas of human scalp hair follicles and found that early-stage hair graying involves matrix hair progenitor depletion linked to P53 pathway activation.
77 citations
,
July 2020 in “Journal of the European Academy of Dermatology and Venereology” This review examines the skin exposome, including solar exposure, air pollution, hormones, nutrition, and psychological factors, but reports no new clinical results.
9 citations
,
November 2013 in “Presse Medicale” This article discusses clinical features and treatment options for hyperandrogenism in women and does not report new findings, highlighting current practices in diagnosis and management.
6 citations
,
February 2012 in “American Journal of Animal and Veterinary Sciences” This review summarizes major growth factors that promote hair follicle growth, but it reports no new experimental findings.
3 citations
,
June 2004 in “Reviews in gynaecological practice” This review reports that treating polycystic ovary syndrome in adolescents with anti-androgens and weight loss is beneficial, and suggests that metformin may be useful for symptom management and prevention.
77 citations
,
March 2021 in “Nature” In this study, increased corticosterone from chronic stress prolonged hair follicle stem cell quiescence in mice, inhibiting regeneration, but restoring Gas6 expression overcame this inhibition.
28 citations
,
May 2017 in “Molecular ecology” This study observed that in wild snowshoe hares, gene expression patterns during seasonal coat color change show a consistent lag between gene expression and visible coat color changes.
1 citations
,
May 2017 in “Maturitas” This review discusses the role of physical activity in healthy aging and reports no clinical results; the authors emphasize the need for integrating exercise into daily life and social settings.
16 citations
,
December 2019 in “Journal of Cellular and Molecular Medicine” This study found that sonicated platelet-rich plasma was more effective than calcium chloride-induced platelet-rich plasma in activating hair follicle stem cells and promoting hair follicle regeneration in mice.
March 2024 in “Drug development & registration” This review highlights the potential of mesenchymal stem cell secretome for developing topical treatments aimed at skin regeneration and treating various diseases, but notes a lack of studies on safety, efficacy, and standardization processes for its clinical use.
14 citations
,
November 2020 in “International Journal of Molecular Sciences” This review article summarizes the potential role of advanced medical therapies—using genes, cells, and/or tissue engineering—in treating various types of alopecia, by examining clinical research, basic studies, and ongoing trials.
14 citations
,
May 2019 in “Experimental Dermatology” In this study, adipose tissue secretome was shown to enhance oxidative stress resistance and promote cell proliferation in vitiligo cells, suggesting a potential natural treatment approach.
11 citations
,
April 2019 in “International Journal of Molecular Sciences” This study found that genetic polymorphisms of OCT1 influence the effectiveness of metformin treatment in improving insulin sensitivity among PCOS patients, suggesting a role for personalized treatment strategies.
1 citations
,
March 2023 in “International Journal of Health and Pharmaceutical Medicine” This review summarizes the link between acne pathogenesis and skin barrier dysfunction, noting that more severe acne correlates with greater skin barrier damage, but reports no new clinical results.
This study found that certain dietary changes, such as a low glycemic load diet for men and specific supplements for women, may improve acne, while chocolate, whey proteins, and dairy products are linked to worsened symptoms in both genders.
4 citations
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March 2017 in “Development” This study found that specialized nipple epidermis in mice is maintained by the repression of TGFβ signaling through estrogen, which highlights the role of hormonal regulation in epidermal maintenance.