53 citations,
March 2014 in “Growth Hormone & IGF Research” IGF-1 injections help mice grow more hair by increasing cell growth and blocking a hair growth inhibitor.
29 citations,
August 2017 in “Skin appendage disorders” IGF-1 may affect hair growth and loss, but more research is needed to confirm effective and safe treatments.
11 citations,
July 2015 in “Gene” DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.
2 citations,
September 2002 in “Journal of Endocrinological Investigation” The GH-IGF-I axis is likely involved in the hormonal imbalances seen in non-obese women with functional hyperandrogenism.
13 citations,
January 2015 in “Evidence-based Complementary and Alternative Medicine” Garlic chive extract helped mice grow more hair by increasing a specific growth factor.
2 citations,
January 2023 in “International Journal of Biological Sciences” A specific pathway involving AR, miR-221, and IGF-1 plays a key role in causing common hair loss.
200 citations,
August 2009 in “Experimental dermatology” Eating high-glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
49 citations,
August 2003 in “Journal of The American Academy of Dermatology” Higher IGF-1 levels in hair follicles link to better finasteride results for hair loss.
39 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
23 citations,
December 2008 in “Current medicinal chemistry” Stimulating sensory neurons can increase IGF-I production, which may help treat various diseases and improve tissue health.
23 citations,
May 1998 in “Journal of Dermatological Science” Insulin or IGF-I is needed for hair growth in newborn mice, while minoxidil helps adult mouse hair grow, suggesting a way to study human hair loss.
13 citations,
October 2013 in “The Journal of Dermatology” Cepharanthine may help hair growth by increasing IGF-I in scalp cells.
6 citations,
March 2016 in “British Journal of Dermatology” Low IGF-1 and high HDL cholesterol levels are linked to more hair loss in middle-aged women.
June 2023 in “Medical records-international medical journal” Decreased IGF-1R expression may contribute to sacrococcygeal pilonidal sinus development.
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February 1999 in “The journal of investigative dermatology/Journal of investigative dermatology” IGF-1 increases whisker growth in transgenic mice.
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26 citations,
June 2000 in “Journal of The American Academy of Dermatology” Men with balding at age 45 had higher IGF-1 and lower IGFBP-3, suggesting these factors might be important in male pattern baldness.
19 citations,
April 2015 in “Stem Cells” Pro-IGF-II improves muscle repair in old mice.
3 citations,
June 2000 in “Journal of The American Academy of Dermatology” Men with balding at age 45 had higher IGF-1 and lower IGFBP-3 levels, suggesting these factors might influence male pattern baldness.
January 2020 in “Menoufia Medical Journal” IGF-1R may play a role in female hair loss and could be a treatment target.
173 citations,
July 1995 in “Biochemical and biophysical research communications” Male hormones promote hair cell growth by using a growth factor from nearby skin cells.
113 citations,
November 2017 in “Scientific Reports” Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.
71 citations,
June 2001 in “American Journal of Pathology” The p53 protein helps control hair follicle shrinking by promoting cell death in mice.
39 citations,
August 2008 in “Growth hormone & IGF research” Raspberry ketone may help grow hair and improve skin elasticity.
32 citations,
February 2024 in “Growth Hormone & IGF Research” Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.
29 citations,
March 2011 in “The Journal of Nutritional Biochemistry” Eating isoflavone can help mice grow hair by increasing a growth factor.
28 citations,
September 2019 in “International Journal of Nanomedicine” Minoxidil nanoparticles can potentially be a more effective treatment for hair growth than current treatments.
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24 citations,
April 2008 in “Fertility and sterility” Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.