5 citations
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January 2012 in “Biological & Pharmaceutical Bulletin” This study found that extract of Hura crepitans inhibited androgen-accelerated NT-4 activity and ameliorated the retardation of hair regrowth in dihydrotestosterone-implanted mice, suggesting a potential role for NT-4 inhibitors in AGA.
4 citations
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March 2017 in “Development” This study found that specialized nipple epidermis in mice is maintained by the repression of TGFβ signaling through estrogen, which highlights the role of hormonal regulation in epidermal maintenance.
3 citations
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June 2004 in “Reviews in gynaecological practice” This review reports that treating polycystic ovary syndrome in adolescents with anti-androgens and weight loss is beneficial, and suggests that metformin may be useful for symptom management and prevention.
2 citations
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September 2004 in “Fertility and sterility” This review discusses the cosmetic and health implications of hirsutism and highlights its potential link to serious underlying disorders, but it presents no new clinical findings.
1 citations
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February 2023 in “Frontiers in Endocrinology” This study demonstrates that combining gene expression data with a random forest algorithm provides highly accurate diagnosis of childhood growth hormone deficiency, showing potential utility in distinguishing it from non-GHD short stature.
1 citations
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January 2022 in “Journal of experimental and clinical medicine” This review examines the relationship between glycation, insulin resistance, and PCOS, discussing various treatments and highlighting M. oleifera and S. platensis as potential therapeutic agents, but reports no new clinical results.
1 citations
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December 2006 in “Burns” New therapies for burn wounds show promise in reducing pain, infection risk, and improving healing and physical outcomes.
1 citations
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November 1996 in “Journal of Cutaneous Medicine and Surgery” Hormones, especially androgens, play a key role in causing acne, and treatments like hormone control pills and hormone-blocking medications can help.
In this review, the authors discuss various skin conditions linked to hyperandrogenism, such as acne and alopecia, with a focus on androgen-targeted therapies, suggesting these are generally more effective than non-androgen-targeted options.
January 2026 in “International Journal of Women s Health” This study found that a nomogram prediction model based on clinical characteristics, bone metabolism, and ovarian function can effectively predict the treatment response to long-acting GnRHa in girls with idiopathic central precocious puberty.
January 2026 in “Archives of Internal Medicine Research” This review examines how regenerative therapies targeting shared biological pathways can promote healing in musculoskeletal disorders and hair follicle dysfunction, highlighting modalities like platelet-rich plasma and laser therapy while addressing challenges in standardization and measurement.
January 2025 in “International Journal of Unani and Integrative Medicine” This review explores hirsutism in women with PCOS, analyzing its pathophysiology and management through both modern medicine and Unani perspectives, and suggests combining these approaches for more holistic care, while calling for future research to enhance treatment efficacy and safety.
November 2024 in “Indian Journal of Animal Health” In this case report, a 7-year-old Labrador with chronic alopecia, weight gain, and dermatitis, was diagnosed with hypothyroidism and treated with levothyroxine and other medications. Improvement, characterized by reduced skin lesions, was observed after two months.
October 2023 in “Frontiers in endocrinology” This review investigates molecular mechanisms behind PCOS pathogenesis and discusses potential therapies, but reports no new clinical results.
October 2023 in “Frontiers in endocrinology” This review examines the role of androgens and androgen receptors in regulating glucose and lipid metabolism, focusing on their effects on mitochondrial content and function; it also discusses the sex-dimorphic influence of androgens and provides theoretical insights into their mechanisms.
March 2023 in “Scholars international journal of obstetrics and gynecology” This article reviews the metabolic and endocrine complexities of PCOS, emphasizing the importance of lifestyle changes and medical management in addressing its various symptoms and complications, but reports no new clinical results.
March 2023 in “Clinical, cosmetic and investigational dermatology” This study suggests that IL-33 promotes hair follicle changes and T cell infiltration in psoriatic mice and humans, contributing to psoriatic alopecia.
January 2023 in “Integrative Journal of Medical Sciences” This report presents a case of a child with hypothyroidism and poorly controlled type 1 diabetes developing both Mauriac syndrome and Van Wyk–Grumbach syndrome, two rare complications.
February 2020 in “Benha Journal of Applied Sciences” This study suggests that high nesfatin-1 levels and insulin resistance are linked to an increased risk and severity of acne vulgaris.
This study found that certain dietary changes, such as a low glycemic load diet for men and specific supplements for women, may improve acne, while chocolate, whey proteins, and dairy products are linked to worsened symptoms in both genders.
January 2018 in “Elsevier eBooks” This chapter reviews various in vitro and laboratory animal models for studying potential therapies for alopecia and reports no new results.
January 2016 in “Springer eBooks” Pubertal acne is linked to hormonal changes, affects quality of life, and is treated similarly to adult acne.
May 2010 in “Current Women's Health Reviews” This article reviews the challenges and importance of diagnosing and managing PCOS, especially in adolescent girls, and reports no new clinical findings; the authors emphasize early intervention.
September 2004 in “Experimental dermatology” This study found that normal murine hair follicles are direct targets for melatonin bioregulation, expressing receptors that are regulated in a hair cycle-dependent manner, influencing keratinocyte apoptosis.
January 2004 in “Online Publication Service of Würzburg University (Würzburg University)” This study found that women with PCOS displayed significantly higher activity of 5alpha-reductase, suggesting an additional role for liver and peripheral tissues in their androgen excess.
January 2004 in “Online Publication Service of Würzburg University (Würzburg University)” This study found that women with PCOS have higher activity of the enzyme 5alpha-reductase, which may contribute to their elevated androgen levels.
93 citations
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February 2009 in “Annals of the New York Academy of Sciences” This review describes the roles of 5α-reductase isozymes in prostate development and pathology and reports no new clinical results.
4 citations
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January 2018 in “Elsevier eBooks” This chapter discusses the sources, classifications, and effects of hormones, their role in disease treatment and food security, and reports no new results.
June 2026 in “International Journal on Science and Technology” This source redefines anti-aging medicine as "precision healthspan pharmacology," suggesting that rather than just treating diseases or accepting aging, pharmacology should focus on expanding functional capacity across various health domains, while emphasizing the importance of fundamental physiological and psychosocial health factors.
In this book, the authors provide an accessible overview of platelet concentrates and their dental applications, highlighting their role in tissue healing and regeneration, and reviewing recent studies on their efficacy in periodontal therapy, implant dentistry, and oral surgery.