research Neuroimmunology of Stress: Skin Takes Center Stage
Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.
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research Both Lesional and Non-Lesional Skin from Acne Patients Shows Robust IL-17-Skewing and Upregulation of Antimicrobial Peptides
Acne patients' skin, both with and without lesions, shows a strong immune response and higher antimicrobial activity.
research Pathophysiological Mechanisms Implicated in Postpartum Depression
Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.
research Functional Enhancement Strategies for Immunomodulation of Mesenchymal Stem Cells and Their Therapeutic Application
New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.
research Plasmacytoid Dendritic Cells in Alopecia Areata: Missing Link?
Plasmacytoid dendritic cells are a key factor in causing hair loss in alopecia areata and could help differentiate it from other hair loss conditions.
research Peroxisome Proliferator Activated Receptor-Gamma Tissue Expression and Gene Polymorphism in Alopecia Areata in an Egyptian Sample
PPAR-γ may be a key target for treating alopecia areata and other skin conditions.
research Dietary Grape Powder Inhibits Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice
Eating grape powder may reduce the severity of skin allergy symptoms.
research Effect of Lithocholic Acid as a Ligand of Vitamin D Receptor on Hair Growth in Alopecia
Lithocholic acid helps hair growth and regeneration in alopecia by activating vitamin D receptors.
research Alopecia Areata: A Review of Disease Pathogenesis
Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.
research Alopecia Areata Profiling Shows TH1, TH2, and IL-23 Cytokine Activation Without Parallel TH17/TH22 Skewing
Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.
research MicroRNA in Skin Diseases
Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.
research Zinc: A Complementary Factor in the Treatment of Chronic Hepatitis C?
Zinc supplementation may help improve treatment outcomes for chronic hepatitis C.
research Topical Mechlorethamine Restores Autoimmune-Arrested Follicular Activity in Mice with an Alopecia Areata-Like Disease by Targeting Infiltrated Lymphocytes
Mechlorethamine treatment regrew hair in mice by killing immune cells causing hair loss without harming hair follicles.
research Old Wine in New Bottles: Reviving Old Therapies for Alopecia Areata Using Rodent Models
Old treatments for other skin conditions showed promise for hair regrowth in mice with a hair loss condition.
research Dengue Virus Infects Primary Human Hair Follicle Dermal Papilla Cells
Dengue virus can infect human hair follicle cells and may cause hair loss.
research Molecular Profiling of Frontal Fibrosing Alopecia Reveals TH1 and JAK-STAT Up-Regulation with No Suppression of Hair Keratins
Frontal fibrosing alopecia shows increased inflammation and JAK-STAT pathway activity without reduced hair proteins.
research Activating an Adaptive Immune Response from a Hydrogel Scaffold Imparts Regenerative Wound Healing
Hydrogel scaffolds can help wounds heal better and grow hair.
research Alopecia Areata: Overview and Insights from January 2018
Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.
research Alopecia Areata: Animal Models Illuminate Autoimmune Pathogenesis and Novel Immunotherapeutic Strategies
Animal models have helped understand hair loss from alopecia areata and find new treatments.
research Type 1 Interferon Signature in the Scalp Lesions of Alopecia Areata
Alopecia areata shows a unique type 1 interferon signature, suggesting potential treatment by targeting this pathway.
research An Overview of JAK/STAT Pathways and JAK Inhibition in Alopecia Areata
Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.
research Autoimmune Polyendocrine Syndrome Type 1: An Italian Survey on 158 Patients
APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.
research Autoantigen Discovery in the Hair Loss Disorder, Alopecia Areata: Implications of Post-Translational Modifications
New protein changes may be involved in the immune attack on hair follicles in alopecia areata.
research Whole Exome Sequencing in Alopecia Areata Identifies Rare Variants in KRT82
Rare changes in the KRT82 gene are linked to a higher risk of Alopecia Areata.
research Toll-Like Receptor 3 Agonist, Polyinosinic-Polycytidylic Acid, Upregulates Carbonic Anhydrase II in Human Keratinocytes
A substance called poly(I:C) increases a protein called carbonic anhydrase II in skin cells, which might help with skin defense and healing.
research Novel Therapies for Alopecia Areata: The Era of Rational Drug Development
New targeted therapies for hair loss from alopecia areata show promise, with personalized treatment expected in the future.
research T-Cell Induced-Self MHC Class I/Peptide Complexes May Enable De Novo Tolerance Induction to Neo-Antigens Occurring Outside of the Thymus
Hair follicles may help teach the immune system to tolerate new self-antigens, but this can sometimes cause hair loss.
research Photoprotective and Immunoregulatory Capacity of Ginsenoside Rg1 in Chronic Ultraviolet B-Irradiated BALB/c Mouse Skin
Ginsenoside Rg1 protects mouse skin from UVB damage and helps control inflammation.
research Anti-Aging Effects of Retinoid Hydroxypinacolone Retinoate on Skin Models
Hydroxypinacolone retinoate is a potent anti-aging ingredient for skin that is more effective and less irritating than other forms of retinoids.
research Melatonin Receptors and Their Role in Human Diseases
Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.