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Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Alopecia areata involves immune system imbalances that may lead to depression and anxiety.

Antidepressants called SSRIs can cause skin problems, bleeding risk, and other side effects.

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.

Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Tamoxifen effectively treats gynecomastia without causing impotence.

Endocrine therapies for cancer significantly increase the risk of hair loss.

Polycystic Ovary Syndrome is common but often undiagnosed, and early treatment is important to prevent health problems.

HIV can cause various nail and hair disorders, important for early diagnosis and treatment.

A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.

Lymphatic vessels are essential for hair follicle growth and skin regeneration.

Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.

Lupus can affect the scalp and nails, often causing hair loss and nail damage, and needs early aggressive treatment to prevent permanent damage.

Stem cells have great potential for improving wound healing, but more research is needed to find the best types and ways to use them.

Autophagy is important for human hair growth and health.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

Mesenchymal stem cells help improve wound healing by reducing inflammation and promoting skin cell growth and movement.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Adrenal disorders can cause lasting brain and behavior issues in children.

Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.