research The Role of Mimicking Growth Factors to Control Anagen Phase: Evaluation In Vitro and In Vivo
Mimicking growth factors in a topical solution can prolong hair growth phase and reduce hair loss without side effects.
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research Clinical Course of the First Japanese Family with Marie Unna Hereditary Hypotrichosis: A Follow-Up Report
The first Japanese family with Marie Unna hereditary hypotrichosis showed hair condition improvement in a child and highlighted the risk of misdiagnosis.
research Telogen Elongation in the Hair Cycle of ob/ob Mice
Obese mice with a leptin gene mutation have a longer resting phase in their hair cycle, which may help understand certain hair loss conditions.
research Methotrexate-Associated Lymphoproliferative Disorder: Sequential Development of Angioimmunoblastic T-Cell Lymphoma-Like Lymphoproliferation in the Lymph Nodes and Diffuse Large B-Cell Lymphoma in the Skin in the Same Patient
Stopping methotrexate might reverse lymphoma-like conditions in some patients.
research The Promoter of an Androgen Dependent Gene in the Hamster Flank Organ
Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.
research Real-Life Effectiveness and Safety of Baricitinib in 17 Japanese Patients With Alopecia Areata: A 60-Week Single Center Study
Baricitinib is effective for treating severe alopecia areata in Japanese patients, but long-term safety needs more study.
research Tribological Properties Between Taut Hair Fibers in Wet Conditions: A New Shampoo Formulation for Eliminating Stick-Slip Friction
Shampoo B, which uses water-soluble silicone, is better at detangling hair in wet conditions due to its two-layer conditioning film.
research Connexin 26 (GJB2) Mutations in Keratitis–Ichthyosis–Deafness Syndrome Presenting with Squamous Cell Carcinoma
Connexin-26 gene mutations may increase cancer risk in KID syndrome patients.
research Diffuse Plate-Like Sheets of Desquamation in a 69-Year-Old Woman with Relapsed Acute Lymphocytic Leukemia
The rash resolved after stopping ponatinib.
research Clinical Snippets: Melanoma Risk Prediction, Monilethrix Mutation, Keratitis-Ichthyosis-Deafness Syndrome, Skin Wrinkling and Lung Aging, Oxidative Stress in Androgenetic Alopecia
Melanoma risk tools need improvement, a gene mutation causes a hair disorder that might be treated by managing cell stress, a potential therapy for a skin-ear disorder involves blocking cell channels, skin wrinkling may indicate lung aging regardless of smoking, and oxidative stress might contribute to common baldness.
research Molecular Mapping of Lymph Node Metastases by Real-Time Reverse Transcription Polymerase Chain Reaction in Two Melanoma Patients
The conclusion is that a certain test might help find cancer spread in lymph nodes for melanoma patients, but more research is needed due to false positives.
research A Case of IFAP Syndrome with Severe Atopic Dermatitis
A baby was diagnosed with IFAP syndrome due to a new genetic mutation, showing severe skin and developmental issues.
research Porokeratotic Eccrine Duct and Hair Follicle Nevus (PEHFN) Associated with Keratitis-Ichthyosis-Deafness (KID) Syndrome
A 15-year-old with KID syndrome developed a rare skin condition called PEHFN.
research Prioritization of Therapy Uncertainties in Congenital Ichthyosis: Results from a Priority Setting Partnership
The top research priorities for congenital ichthyosis include long-term side effects of oral retinoids, best topical treatments, and treatments for itch and hair loss.
research A Novel Small Compound HPH-15 Antagonizes TGF-β/Smad Signaling and Ameliorates Experimental Skin Fibrosis
HPH-15, a new compound, effectively reduces skin fibrosis in experiments without causing harm.
research Inherited Ichthyoses: Generalized Mendelian Disorders of Cornification
Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.
research KGS1 Kamishoyosangoshimotsuto Extract Tablets Improved Skin Condition and Hair Properties
KGS1 tablets improved skin and hair health.
research Genome-Wide Association Study in Japanese Females Identifies Fifteen Novel Skin-Related Trait Associations
Researchers found 15 new genetic links to skin traits in Japanese women.
research Lamellar Ichthyosis: One Case Report
Treatment with moisturizers improved the skin condition of a girl with a rare genetic skin disorder.
research Identification of Anabolic Selective Androgen Receptor Modulators with Reduced Activities in Reproductive Tissues and Sebaceous Glands
Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.
research LB789 Novel IFNγ Aptamer TAGX-0003 Protected Hair Follicles from Immune Privilege Collapse and Reversed Alopecia Areata-Like Phenotype in Humanized Mouse Model
TAGX-0003 protected hair follicles and reversed alopecia areata in a mouse model.
research Spironolactone Therapy for Hyperandrogenic Anovulatory Women: Clinical and Endocrinological Study
Spironolactone improved symptoms in women with hormonal imbalances and had few side effects.
research Acquired Ichthyosis, Alopecia, and Loss of Hair Pigment Associated with Leiomyosarcoma
A woman's skin and hair conditions improved after her cancerous tumor was removed.
research Roles of Two Sphingomyelin Synthase Isoforms in Murine Hair
Both SMS1 and SMS2 are crucial for normal hair growth and cycle in mice.
research Autosomal Recessive Congenital Ichthyosis Due to PNPLA1 Mutation in a Golden Retriever–Poodle Cross-Bred Dog and the Effect of Topical Therapy
Long-term oral and topical treatments improved skin condition in a goldendoodle with a genetic disorder.
research Pro-Insulin-Like Growth Factor-II Ameliorates Age-Related Inefficient Regenerative Response by Orchestrating Self-Reinforcement Mechanism of Muscle Regeneration
Pro-IGF-II improves muscle repair in old mice.
research Matriptase Activation and Shedding with HAI-1 Induced by Steroid Sex Hormones in Human Prostate Cancer Cells, but Not in Breast Cancer Cells
Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.
research Semidominant Inheritance in Epidermolytic Ichthyosis
Epidermolytic ichthyosis can be inherited in a semidominant way with mild symptoms in carriers.
research Advanced Glycation End-Products Inhibit Mesenchymal-Epidermal Interaction by Up-Regulating Proinflammatory Cytokines in Hair Follicles
AGEs may cause hair loss by increasing inflammation in hair follicles.
research A Single Intradermal Injection of Autologous Adipose-Derived Stem Cells Rejuvenates Aged Skin and Sharpens Double Eyelids
Injecting a person's own fat stem cells into their skin can make it look younger and improve double eyelids for over a year.