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Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

The leaves of Platycladus orientalis have potential health benefits but require more research for safety and understanding how they work.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

Compounds from Angelica koreana roots, especially osthenol, could be effective for treating conditions like prostate disease and hair loss.

Rumex japonicus Houtt. may be an effective treatment for atopic dermatitis by reducing inflammation.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.

New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.

Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.

Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.

Topical finasteride doesn't reduce DHT levels, hinting at an endocrine role in hair loss.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.

Over 150 new molecules with biological activities were found in traditional herbal medicines, some with potential for new drug development.

Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

Cuscuta reflexa extracts and an isolate promoted hair growth and could be natural treatments for hair loss.

Ritlecitinib shows promise as a versatile treatment for various autoimmune and inflammatory diseases.

Optimal long-acting finasteride injection dose found: 16.8 mg, effective for one month.

A new compound from a sponge strongly inhibits an enzyme linked to male-pattern hair loss without being toxic at low levels.

A new compound shows promise as a topical treatment for hair loss.

Citrullus colocynthis fruit extract and its compound may help treat enlarged prostate.

Versican is important for hair growth and could help find new hair regrowth treatments.

Spin traps like PBN could protect skin from pollution and sunlight in cosmetics but need more research for safe use.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.

The hair-growth formula with L-cystine helps protect and grow hair cells.

The review concludes that the Ziziphus species, especially jujube, may promote hair growth and have various health benefits, warranting more research.