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5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Minoxidil activates hair growth by being sulfated by P-PST in the human liver.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Applying a specific inhibitor lightens skin and hair color.

Testosterone may slow down wound healing and increase inflammation.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Ginseng, especially red ginseng, may help regrow hair and block a hair loss-related enzyme.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Genes and hormones cause hair loss, with four genes contributing equally.

Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Some plants may help with hair growth and have fewer side effects than synthetic drugs, but more research is needed to confirm their effectiveness.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.