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In this case study, zinc deficiency persisted despite supplementation in a patient with severe malnutrition and empyema, potentially due to nutrient absorption competition and proton pump inhibitor use.

This report describes a case of hypozincemia type-II in an exclusively breast-fed infant, which resolved with zinc therapy and weaning, highlighting genetic factors in zinc transporter gene SLC30A2.

In this study, researchers found that patients undergoing one-anastomosis gastric bypass experienced a greater incidence of low serum zinc levels and related symptoms, such as hair loss and delayed wound healing, compared to those undergoing sleeve gastrectomy.

This article reviews the clinical manifestations and contributing factors of acute zinc depletion syndrome, reporting no new results but discussing prevention and treatment strategies.

This article discusses various clinical presentations and underlying mechanisms of zinc deficiency but reports no new research findings; biochemical signs often precede clinical symptoms.

This article reviews the potential of Acyzol, a zinc-containing drug, to treat and prevent zinc deficiency conditions, but it reports no new clinical findings.

This article reviews zinc deficiency disorders, highlighting their clinical features and treatment with zinc therapy, but reports no new clinical results.

This study observed that lower serum zinc levels in patients with chronic liver disease were linked to a higher prevalence of symptoms like dermatitis, taste disorder, and alopecia, suggesting these symptoms may be associated with zinc deficiency.

This study found that young healthy women with a family history of noninsulin-dependent diabetes mellitus exhibited higher zinc and lower copper concentrations in hair compared to those without such a family history, suggesting a possible Cu-Zn antagonism.

Zinc deficiency is linked to respiratory infections in children.

This fact sheet discusses the impacts of zinc deficiency, including its effects on the immune system, cognitive function, and growth in children, and highlights the increased risk for those who consume alcohol excessively; it reports no new clinical results.

This article discusses zinc deficiency in animal nutrition and highlights the need for zinc supplementation in livestock diets; it reports no new study results.

In this study, oral zinc sulphate was found to cause hair hypopigmentation and significantly inhibit eumelanogenesis in mice.

This review found a predominance of low serum zinc levels across various skin disorders, indicating possible value in further investigating zinc supplementation as an adjunctive therapy.

This study found that zinc levels in hospitalized patients with significant weight loss did not correlate with taste perception or vitamin A status, even in those with reduced taste acuity.

This study found that serum zinc levels were significantly decreased in obese women with polycystic ovary syndrome compared to their non-obese counterparts.

This study concluded that hair zinc levels in weaned male rats do not reliably indicate their overall zinc status, as varying dietary zinc levels produced inconsistent hair zinc concentrations.

In this study, oral zinc supplementation for twelve weeks increased serum zinc levels in alopecia areata patients with low zinc, showing positive hair regrowth in 66.7% of participants, though this was not statistically significant.

In this study, a syndrome of zinc deficiency was observed in adults receiving intravenous feeding, with zinc supplementation improving symptoms except for delayed hair regrowth.

This article reports two cases where zinc deficiency caused by excessive bowel resection and parenteral nutrition led to skin lesions that improved rapidly with zinc sulfate supplementation.

In this study, zinc supplementation rapidly improved conditions such as anorexia, depression, and foot soreness in sheep and goats diagnosed with zinc deficiency, along with healing skin lesions and resumption of hair and wool growth.

This report describes two cases where acquired zinc deficiency was associated with skin symptoms like hair loss and eczema, suggesting a recognizable syndrome in zinc-deficient patients.

This study reports two cases of acquired zinc deficiency presenting with skin symptoms such as hair loss and acrodermatitis, suggesting these manifestations may help in diagnosing zinc deficiency in humans.

This animal study found that second generation mice exposed to excess zinc during gestation and lactation had reduced plasma copper, body weight, and hematocrit, with lighter and delayed hair development compared to mice on a normal zinc diet.

This study found that serum zinc levels were lower in PCOS subjects compared to normal controls, suggesting zinc may play a vital role in PCOS pathophysiology.

This narrative review explores existing evidence on zinc's impact in certain immune-related, gastrointestinal, dermatological, and metabolic disorders, considering clinical and observational studies to assess zinc supplementation's clinical relevance.