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Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Lactate production is important for activating hair growth stem cells.

Stem cell niches support, regulate, and coordinate stem cell functions.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

Oxidative stress affects hair loss in men with androgenetic alopecia.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

ADSC-CM treatment improved hair density and thickness in women with hair loss, safely and effectively.

Hair follicle regeneration needs special conditions and young cells.

Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Fat from the body can help improve hair growth and scars when used in skin treatments.

Photothermal hydrogels are promising for infection control and tissue repair, and combining them with other treatments could improve results and lower costs.

Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.

Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.

New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.

Botox increased hair count in men with baldness and might work by improving scalp blood flow.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Botulinum toxin has potential for treating various skin conditions and improving wound healing.