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30-60 / 1000+ resultsresearch Immunohistochemical Analysis of the Mechanistic Target of Rapamycin and Hypoxia Signalling Pathways in Basal Cell Carcinoma and Trichoepithelioma
The study found that analyzing certain cell signaling pathways is not a reliable method to tell apart two types of skin tumors.
![Hypoxia Treatment of Adipose Mesenchymal Stem Cells Promotes the Growth of Dermal Papilla Cells via HIF-1α and ERK1/2 Signaling Pathways](/images/research/a6dd81cd-59f1-4cbd-8b3d-2b42a3b7386d/small/19066.jpg)
research Hypoxia Treatment of Adipose Mesenchymal Stem Cells Promotes the Growth of Dermal Papilla Cells via HIF-1α and ERK1/2 Signaling Pathways
Treating fat stem cells with low oxygen boosts hair growth cell growth through specific signaling pathways.
![HIF-1α Stimulators Function Equally to Leading Hair Loss Agents in Enhancing Dermal Papilla Growth](/images/research/13daa333-5dc2-4687-a369-5b0027e0353a/small/13291.jpg)
research HIF-1α Stimulators Function Equally to Leading Hair Loss Agents in Enhancing Dermal Papilla Growth
HIF-1α stimulators, like deferiprone, work as well as popular hair loss treatments, minoxidil and caffeine, in promoting hair growth.
![FLCN regulates transferrin receptor 1 transport and iron homeostasis](/images/research/18ed5978-0b1e-4ec9-9691-7ce6aba84880/small/31052.jpg)
research FLCN regulates transferrin receptor 1 transport and iron homeostasis
FLCN helps control iron levels in cells.
![Functional enhancement strategies for immunomodulation of mesenchymal stem cells and their therapeutic application](/images/research/d7a108db-f6ce-4da7-8a69-e3900884e01c/small/22881.jpg)
research Functional enhancement strategies for immunomodulation of mesenchymal stem cells and their therapeutic application
New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.
![Analysis of the FGF gene family provides insights into aquatic adaptation in cetaceans](/images/research/ca29c64b-8901-4442-aa7a-4b9093228a3d/small/30882.jpg)
research Analysis of the FGF gene family provides insights into aquatic adaptation in cetaceans
Whale genes show changes that help them live in water, like less hair and better flippers.
![256 Expression patterns of the Siah genes in postnatal mouse skin](/images/research/24ee9768-e95b-48b8-890e-34cbc6bcee67/small/18121.jpg)
research 256 Expression patterns of the Siah genes in postnatal mouse skin
The Siah1 and Siah2 genes are active in mouse skin development and hair growth, especially right after birth.
![Biomaterials Functionalized with MSC Secreted Extracellular Vesicles and Soluble Factors for Tissue Regeneration](/images/research/ba93561a-69e0-4640-b70d-6c946f2a2bb6/small/35325.jpg)
research Biomaterials Functionalized with MSC Secreted Extracellular Vesicles and Soluble Factors for Tissue Regeneration
Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.
![Improving translational research in sex-specific effects of comorbidities and risk factors in ischaemic heart disease and cardioprotection: position paper and recommendations of the ESC Working Group on Cellular Biology of the Heart](/images/research/b1c36f06-8e61-4175-bb0b-02926624f306/small/17470.jpg)
research Improving translational research in sex-specific effects of comorbidities and risk factors in ischaemic heart disease and cardioprotection: position paper and recommendations of the ESC Working Group on Cellular Biology of the Heart
The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.
![Quercitrin Stimulates Hair Growth with Enhanced Expression of Growth Factors via Activation of MAPK/CREB Signaling Pathway](/images/research/013c39ab-777f-4083-9421-39807b84c678/small/22887.jpg)
research Quercitrin Stimulates Hair Growth with Enhanced Expression of Growth Factors via Activation of MAPK/CREB Signaling Pathway
Quercitrin may help treat hair loss by promoting hair growth and improving cell health.
![Mammalian Fetal Organ Regeneration](/images/research/19481cb7-e0fa-465c-9806-8dc0c6c88fa3/small/20020.jpg)
research Mammalian Fetal Organ Regeneration
Fetal wounds heal without scarring because of different biological factors, which could help improve adult wound healing.
![(Neuro-)endocrinology of epithelial hair follicle stem cells](/images/research/9f993e96-6c55-42a5-9501-05dc462b0eed/small/24831.jpg)
research (Neuro-)endocrinology of epithelial hair follicle stem cells
Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.
![Proposed mechanisms of low-level light therapy in the treatment of androgenetic alopecia](/images/research/881f2659-9e6d-4c01-acc5-212d915e5c44/small/5251.jpg)
research Proposed mechanisms of low-level light therapy in the treatment of androgenetic alopecia
LLLT helps treat hair loss by increasing blood flow, reducing inflammation, and stimulating growth factors.
![Basic mechanisms of SARS-CoV-2 infection. What endocrine systems could be implicated?](/images/research/854aaf82-f1a7-4613-a0f4-d57dd4fecf05/small/13187.jpg)
research Basic mechanisms of SARS-CoV-2 infection. What endocrine systems could be implicated?
SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.
![Ultraviolet B Preconditioning Enhances the Hair Growth-Promoting Effects of Adipose-Derived Stem Cells Via Generation of Reactive Oxygen Species](/images/research/621ee789-1b3e-47b0-9e17-44bb4ce07605/small/23142.jpg)
research Ultraviolet B Preconditioning Enhances the Hair Growth-Promoting Effects of Adipose-Derived Stem Cells Via Generation of Reactive Oxygen Species
Low-dose UVB light improves hair growth effects of certain stem cells by increasing reactive oxygen species.
research DNA Damage-Inducible Transcript 4 Is an Innate Surveillant of Hair Follicular Stress in Vitamin D Receptor Knockout Mice and a Regulator of Wound Re-Epithelialization
Vitamin D receptor is important for regulating hair growth and wound healing in mice.
![The Use of Adipose-Derived Stem Cells in Selected Skin Diseases (Vitiligo, Alopecia, and Nonhealing Wounds)](/images/research/ea1646d3-d851-41be-8bd3-609491267b80/small/18357.jpg)
research The Use of Adipose-Derived Stem Cells in Selected Skin Diseases (Vitiligo, Alopecia, and Nonhealing Wounds)
Adipose-derived stem cells show promise in treating skin conditions like vitiligo, alopecia, and nonhealing wounds.
![Wound Healing: A Cellular Perspective](/images/research/9dde12dd-3934-4b3b-bec6-e0b163969845/small/19385.jpg)
research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
![Molecular Mechanisms Responsible for Therapeutic Potential of Mesenchymal Stem Cell-Derived Secretome](/images/research/e2c11517-019a-4420-a18a-446fb5147f0f/small/15889.jpg)
research Molecular Mechanisms Responsible for Therapeutic Potential of Mesenchymal Stem Cell-Derived Secretome
The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.
![Chapter 6 Fetal Skin Wound Healing](/images/research/cd1ccdb1-4706-4782-8e36-a172f726c873/small/19939.jpg)
research Chapter 6 Fetal Skin Wound Healing
Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.
![Review of Hair Follicle Dermal Papilla cells as <i>in vitro</i> screening model for hair growth](/images/research/3cd6ce89-2a40-485c-8c45-59fd1ffe3d72/small/13740.jpg)
research Review of Hair Follicle Dermal Papilla cells as in vitro screening model for hair growth
Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
![Role of Growth Factors-Rich Plasma, Gel and Membrane in Dermal Wound Healing and Injured Tissue Restoration and Regeneration](/images/research/22c3d8ff-804c-477b-b276-eda991597a6a/small/17081.jpg)
research Role of Growth Factors-Rich Plasma, Gel and Membrane in Dermal Wound Healing and Injured Tissue Restoration and Regeneration
Growth factors-rich plasma treatments can significantly speed up wound healing and tissue regeneration.
![Co-opting Developmental Signaling Pathways to Promote Wound Healing](/images/research/0bf70a80-909a-4246-babf-60e2da69a49e/small/19487.jpg)
research Co-opting Developmental Signaling Pathways to Promote Wound Healing
Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.
![Regenerative Medicine of Epidermal Structures](/images/research/15b2f64d-a2a9-4dc3-b0fb-06d107dc3121/small/26095.jpg)
research Regenerative Medicine of Epidermal Structures
New treatments for skin and hair repair show promise, but further improvements are needed.
![258 11β-hydroxysteroid dehydrogenase type 1 inhibition attenuates the adverse effects of glucocorticoids on dermal papilla cells](/images/research/ed2412fe-feaf-492c-a172-92d1d7beabc2/small/18131.jpg)
research 258 11β-hydroxysteroid dehydrogenase type 1 inhibition attenuates the adverse effects of glucocorticoids on dermal papilla cells
Blocking a specific enzyme can reduce the negative impact of stress hormones on hair growth cells.
research Efficacy and Tolerability of a Topical Gel Containing Mimicking Growth Factors Oligopeptides, Caffeine, Taurine and an Iron-Chelating Complex in Subjects with Androgenetic Alopecia Treated with Topical Minoxidil or Oral Finasteride: a Prospective, 6-Month, Randomized, Assessor-Blinded, 4-Arm, Parallel Group Study
![Stroke Recovery](/images/research/23b69d45-23e4-4749-957d-04397f7d9012/small/21826.jpg)
research Stroke Recovery
Transplanted human Olig2+ astroglia may help improve learning and memory after a stroke.
![Slowly Does It](/images/research/15a551ad-c1d2-46c7-8972-d5ddf719f19d/small/21822.jpg)
research Slowly Does It
Special astrocytes improved learning and memory in rats after a stroke.
![Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine](/images/research/cba46098-5dc7-45d3-90d7-9766670849d8/small/16062.jpg)
research Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine
The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.