September 2017 in “Journal of Investigative Dermatology” Certain miRNAs might be involved in a hair loss condition called frontal fibrosing alopecia and could possibly help in its diagnosis.
55 citations,
April 2010 in “Cancer and Metastasis Reviews” TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.
December 2023 in “International journal of multidisciplinary research and analysis” SH-MSCs gel reduced IL-6 and increased TGF-β, suggesting it could treat alopecia.
April 2018 in “Journal of Investigative Dermatology” The document concludes that ERBB2 mutations are common in extramammary Paget disease and may respond to systemic treatments like cancer immunotherapy.
2 citations,
April 2018 in “Journal of Investigative Dermatology” Intralesional chemotherapy with 5-fluorouracil and methotrexate may worsen keratoacanthoma-type skin cancer in transplant patients.
April 2018 in “Journal of Investigative Dermatology” FOL-005, a hair growth promoter, acts locally on mouse skin where injected and could be a promising hair loss treatment.
April 2018 in “Journal of Investigative Dermatology” Higher levels of nidogen1 and type IV collagen are found in basal cell carcinoma compared to normal skin.
9 citations,
May 2021 in “Immunological Reviews” Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.
19 citations,
April 2015 in “European Journal of Pharmacology” Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.
10 citations,
August 2023 in “Advanced Science” Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.
56 citations,
June 2015 in “Nature Protocols” Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.
23 citations,
December 2013 in “Regenerative Medicine” Hair follicle culture helps develop new treatments for hair loss.
April 2024 in “The Journal of experimental medicine/The journal of experimental medicine” Treg cells help repair and regenerate tissues by interacting with local cells.
28 citations,
May 2019 in “Life Sciences” Ginsenoside Rb1 from Panax ginseng helps mink hair grow by activating certain cell signals.
17 citations,
May 2018 in “PeerJ” VB-1, a natural compound, may promote hair growth by enhancing a key cell growth pathway.
46 citations,
December 2018 in “Genes & Development” Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.
8 citations,
October 2020 in “Stem cell research & therapy” DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.
466 citations,
June 2009 in “Experimental dermatology” We now understand more about what causes acne and this could lead to better, more personalized treatments.
49 citations,
November 2021 in “Annual review of pathology” Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.
48 citations,
June 2020 in “Current Rheumatology Reports” Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.
April 2010 in “The Journal of Urology” Human prostate cells produce more WISP1/CCN4 when there's not enough oxygen.
April 2010 in “The Journal of Urology” Hair loss, prostate size, and urinary issues are related due to androgen effects.
17 citations,
January 2010 in “PubMed” Optimal storage solutions and effective additives are crucial for improving the survival of hair transplant grafts.
14 citations,
March 2022 in “Journal of Biomedical Science” Cyanidin 3-O-arabinoside may help treat a common form of hair loss by protecting cells against aging and improving cell function.
11 citations,
September 2019 in “Dermatologic Surgery” A substance called Vascular Endothelial Growth Factor can protect certain hair follicle stem cells from damage caused by androgens, suggesting a new possible treatment for hair loss.
1 citations,
June 2021 in “Biomolecules & Therapeutics” Activating δ-opioid receptors can help hair grow.
26 citations,
August 2019 in “Stem Cell Research & Therapy” PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.
May 2023 in “Frontiers in Cell and Developmental Biology” The document concludes that using stem cells to regenerate hair follicles could be a promising treatment for hair loss, but there are still challenges to overcome before it can be used clinically.
March 2023 in “International Journal of Molecular Sciences” ADSC-Exos with miR-122-5p can help treat hair loss by promoting hair growth.
343 citations,
December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.