research Polycystic Ovary Syndrome in Adolescents
PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.
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research Progress and Prospects: Gene Therapy for Performance and Appearance Enhancement
Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.
research Hormonal Treatment of Acne Vulgaris: An Update
Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.
research Clinical Characterization of Men with Long QT Syndrome and Torsades de Pointes Associated with Hypogonadism: A Review and Pharmacovigilance Study
Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.
research Melatonin Membrane Receptors in Peripheral Tissues: Distribution and Functions
Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
research Placental mRNA Expression of Neurokinin B Is Increased in PCOS Pregnancies with Female Offspring
Pregnant women with PCOS have higher levels of Neurokinin B in the placenta, especially with female babies.
research Linking Diet to Acne Metabolomics, Inflammation, and Comedogenesis: An Update
Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.
research Outcome of Long-Term Treatment with the 5α-Reductase Inhibitor Finasteride in Idiopathic Hirsutism: Clinical and Hormonal Effects During a 1-Year Course of Therapy and 1-Year Follow-Up
Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.
research Effects of Subchronic Finasteride Treatment and Withdrawal on Neuroactive Steroid Levels and Their Receptors in the Male Rat Brain
Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.
research The Need and Management of Hormone Imbalances in Women
Balanced hormones are crucial for women's health, and can be managed with lifestyle changes or hormone therapy if needed.
research Nonclassic Congenital Adrenal Hyperplasia: Pathophysiology, Genetics, and Management
Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.
research Precocious Puberty in a 24-Month-Old Nigerian Girl: Case Report
A 24-month-old Nigerian girl developed early puberty with no family history, needing treatment her family couldn't afford.
research The Dihydrotestosterone Hypothesis of Prostate Cancer and Its Therapeutic Implications
The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
research Hyposecretion of the Adrenal Androgen Dehydroepiandrosterone Sulfate (DHEA-S) in the Majority of Alopecia Areata Patients: Is It a Primitive and Pathogenic Perturbation of the Hypothalamic-Pituitary-Adrenal Axis?
Low DHEA-S levels might be linked to alopecia areata and could be a potential treatment target.
research Local Injection of Triamcinolone Acetonide: A Forgotten Etiology of Cushing’s Syndrome
Injecting steroids like Triamcinolone Acetonide for skin treatments can cause Cushing's Syndrome.
research Pathways to Inflammation: Acne Pathophysiology
Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.
research Age-Related Changes in Endogenous Glucocorticoids, Gonadal Steroids, Endocannabinoids, and Their Ratios in Plasma and Hair from Male C57BL/6 Mice
Male C57BL/6 mice show age-related fluctuations in certain hormones and their ratios in both blood and hair.
research Assessing the Role of Stressful Life Events in the Induction and Recurrence of Alopecia Areata: A Case-Control Study
Stress can trigger or worsen alopecia areata.
research Involvement of Neurosteroids in the Control of Hypothalamic-Pituitary-Adrenal Axis Activity in Pregnant Sheep Under Basal and Stressful Conditions
Neurosteroids play a key role in controlling the brain-adrenal gland activity in pregnant sheep, both in normal and stressful situations.
research Hair Cortisol in Polycystic Ovary Syndrome
Women with PCOS have higher hair cortisol levels, which are linked to worse metabolic and inflammatory conditions.
research Consideration When Interpreting Outpatient Data
Objective assessment is needed to accurately determine medication use and adherence.
research Management Approaches to Congenital Adrenal Hyperplasia in Adolescents and Adults: Latest Therapeutic Developments
Glucocorticoid and mineralocorticoid therapy effectively manage Congenital Adrenal Hyperplasia symptoms but have limitations.
research Steroid Biomarkers and Genetic Studies Reveal Inactivating Mutations in Hexose-6-Phosphate Dehydrogenase in Patients with Cortisone Reductase Deficiency
Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.
research Generalized Glucocorticoid Resistance
Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.
research Qiviut Cortisol Reflects Hypothalamic–Pituitary–Adrenal Axis Activity in Muskoxen (Ovibos Moschatus)
Muskoxen's qiviut cortisol levels indicate their stress hormone activity over the hair growth period.
research Frontiers in the Neuroendocrine Controls of Hair Growth
Hair growth and health are influenced by stress and hormones.
research Targeting the Pre-Receptor Metabolism of Cortisol as a Novel Therapy in Obesity and Diabetes
Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.
research Hair Follicle as a Target of Stress Hormones and Autoimmune Reactions
Stress hormones and autoimmune reactions can cause hair loss.
research The Local Hypothalamic–Pituitary–Adrenal Axis in Cultured Human Dermal Papilla Cells
Stress hormone CRF causes hair loss and inhibits hair growth in human cells.
research The Local Hypothalamic–Pituitary–Adrenal Axis in Cultured Human Dermal Papilla Cells
Stress hormone CRF causes hair loss and stops hair cell growth.