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The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

The rat model showed early perimenopause with regular cycles and low hormones, and late perimenopause with irregular cycles and higher hormone levels.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.

Higher BMI and lower testosterone are linked to more aggressive prostate cancer.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.

Pubertal acne is linked to hormonal changes, affects quality of life, and is treated similarly to adult acne.

Identifying nonclassic congenital adrenal hyperplasia and carriers of CYP21 mutations is challenging, and genetic counseling is recommended due to their prevalence.

Early NAS level changes affect alcohol consumption vulnerability.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.

New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.

Geriatric Julia Creek dunnarts often suffer from reproductive and skin diseases, impacting conservation efforts.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

High levels of ST14 and TMEFF1 proteins in ovarian cancer are linked to worse patient outcomes and may be a new treatment target.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

Finasteride helps treat prostate issues and may prevent prostate cancer in high-risk men.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Gene mutations can cause problems in male genital development.

New genes and pathways are important for testosterone production and male sexual development.

Medical treatments like chemotherapy and radiotherapy can harm sperm production, so freezing sperm before treatment is important for men who want children later.