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In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Certain metabolites are lower in women with PCOS and could be potential markers for the condition.

Certain hormone treatments can improve acne and related conditions in women.

Finasteride reduces alcohol withdrawal effects, especially in female mice.

Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.

The exact cause of growth hormone-responsive alopecia in dogs is unclear.

Adrenal gland disease is common in ferrets and causes hair loss and other symptoms.

Dosing time affects finasteride's effectiveness and safety in rats.

Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.

Identifying nonclassic congenital adrenal hyperplasia and carriers of CYP21 mutations is challenging, and genetic counseling is recommended due to their prevalence.

Dexamethasone affects hair growth by altering levels of proteins that either promote or inhibit hair follicle growth.

New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.

PCOS may increase the risk of certain cancers.

PCOS is linked to a higher risk of endometrial cancer but not ovarian or breast cancer, and more research is needed on its role in cancer development and treatment effects.

Pubertal acne is linked to hormonal changes, affects quality of life, and is treated similarly to adult acne.

A postmenopausal woman's facial redness, acne, and excess hair were caused by too much hormone therapy for insomnia, but improved after stopping the treatment.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.